3440-28-6
Chemical Structure
Betamipron
Synonym(s): N-Benzoyl-β-alanine
- CAS No.: 3440-28-6
- Formula:C10H11NO3
- Molecular Weight:193.20
IUPAC Name: 3-benzamidopropanoic acid
InChIKey: CWXYHOHYCJXYFQ-UHFFFAOYSA-N
SMILES: O=C(O)CCNC(C1=CC=CC=C1)=O
Biological Activity: Betamipron (N-benzoyl-β-alanine) is a carbapenem β-lactam antibiotic with antibacterial activity against most Gram-positive and Gram-negative aerobic and anaerobic bacteria. Betamipron can target and inhibit renal organic anion transporters, alleviate renal injury caused by Cisplatin (HY-17394), without interfering with the biological activity of cisplatin. Betamipron is often used in combination with panipenem, which can attenuate the renal effects induced by panipenem and slightly promote the proliferation of Clostridium difficile in the cecum. Betamipron can be used in studies related to renal injury and bacterial infection[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Betamipron | 98.69% | Betamipron (N-benzoyl-β-alanine) is a carbapenem β-lactam antibiotic with antibacterial activity against most Gram-positive and Gram-negative aerobic and anaerobic bacteria. Betamipron can target and inhibit renal organic anion transporters, alleviate renal injury caused by Cisplatin (HY-17394), without interfering with the biological activity of cisplatin. Betamipron is often used in combination with panipenem, which can attenuate the renal effects induced by panipenem and slightly promote the proliferation of Clostridium difficile in the cecum. Betamipron can be used in studies related to renal injury and bacterial infection. | ||||||||||||||||||||
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Betamipron (Standard) | ≥98% | Betamipron (Standard) is the analytical standard of Betamipron (HY-B1127). This product is intended for research and analytical applications. Betamipron (N-benzoyl-β-alanine) is a carbapenem β-lactam antibiotic with antibacterial activity against most Gram-positive and Gram-negative aerobic and anaerobic bacteria. Betamipron can target and inhibit renal organic anion transporters, alleviate renal injury caused by Cisplatin (HY-17394), without interfering with the biological activity of cisplatin. Betamipron is often used in combination with panipenem, which can attenuate the renal effects induced by panipenem and slightly promote the proliferation of Clostridium difficile in the cecum. Betamipron can be used in studies related to renal injury and bacterial infection. | ||||||||||||||||||||
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- [1]. Watanabe K, et al. In vitro antibacterial activity of a new carbapenem, panipenem, against anaerobic bacteria[J]. Chemotherapy, 1991, 39(Suppl 3): 46-54.
- [2]. Tokunaga J, et al. Betamipron reduces cisplatin nephrotoxicity in rodents without modifying its antileukemic activity in mice. Ren Fail. 1997;19(3):425-438. [Content Brief]
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