353495-22-4
353495-22-4
Chemical Structure
Phox-I2
- CAS No.: 353495-22-4
- Formula:C18H15N3O4
- Molecular Weight:337.33
IUPAC Name: 8-nitro-4-(3-nitrophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
InChIKey: PADQUVZDTGNTLH-UHFFFAOYSA-N
SMILES: O=[N+]([O-])C1=CC(C2NC3=C(C4C2CC=C4)C=C(C=C3)[N+]([O-])=O)=CC=C1
Biological Activity: Phox-I2 is a selective inhibitor of p67phox-Rac1 interaction, binds to p67phox with high affinity with a Kd of ~150 nM. Phox-I2 is a NADPH oxidase 2 (NOX2) inhibitor and inhibits reactive oxygen species (ROS) production[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Phox-I2 | 99.46% | Phox-I2 is a selective inhibitor of p67phox-Rac1 interaction, binds to p67phox with high affinity with a Kd of ~150 nM. Phox-I2 is a NADPH oxidase 2 (NOX2) inhibitor and inhibits reactive oxygen species (ROS) production. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.80
HY-W327122BAP1-IN-1 -
Similarity Score 0.73
HY-W549903p67phox-IN-1 -
Similarity Score 0.64
HY-170393iBFAR2 -
Similarity Score 0.61
HY-1100874BP-TQS -
Similarity Score 0.61
HY-117611GAT107 -
Similarity Score 0.61
HY-167922(R,R,S)-GAT107 -
Similarity Score 0.58
HY-W436420WAY-299375 -
Similarity Score 0.57
HY-138686GPR30 agonist-1 -
Similarity Score 0.56
HY-107682TQS -
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