1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. nAChR
  3. 4BP-TQS

4BP-TQS is a potent allosteric agonist of α7 nAChR. 4BP-TQS activates nAChRs via an allosteric transmembrane site.

For research use only. We do not sell to patients.

4BP-TQS Chemical Structure

4BP-TQS Chemical Structure

CAS No. : 360791-49-7

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Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO USD 88 In-stock
Solid
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10 mg USD 130 In-stock
25 mg USD 260 In-stock
50 mg USD 410 In-stock
100 mg USD 650 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

4BP-TQS is a potent allosteric agonist of α7 nAChR. 4BP-TQS activates nAChRs via an allosteric transmembrane site[1].

Molecular Weight

405.31

Formula

C18H17BrN2O2S

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=S(N)(C1=CC=C2NC(C3CC=CC3C2=C1)C4=CC=C(C=C4)Br)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (616.81 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4672 mL 12.3362 mL 24.6725 mL
5 mM 0.4934 mL 2.4672 mL 4.9345 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4672 mL 12.3362 mL 24.6725 mL 61.6812 mL
5 mM 0.4934 mL 2.4672 mL 4.9345 mL 12.3362 mL
10 mM 0.2467 mL 1.2336 mL 2.4672 mL 6.1681 mL
15 mM 0.1645 mL 0.8224 mL 1.6448 mL 4.1121 mL
20 mM 0.1234 mL 0.6168 mL 1.2336 mL 3.0841 mL
25 mM 0.0987 mL 0.4934 mL 0.9869 mL 2.4672 mL
30 mM 0.0822 mL 0.4112 mL 0.8224 mL 2.0560 mL
40 mM 0.0617 mL 0.3084 mL 0.6168 mL 1.5420 mL
50 mM 0.0493 mL 0.2467 mL 0.4934 mL 1.2336 mL
60 mM 0.0411 mL 0.2056 mL 0.4112 mL 1.0280 mL
80 mM 0.0308 mL 0.1542 mL 0.3084 mL 0.7710 mL
100 mM 0.0247 mL 0.1234 mL 0.2467 mL 0.6168 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
4BP-TQS
Cat. No.:
HY-110087
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