3564-96-3
Chemical Structure
Piperitenone oxide
- CAS No.: 3564-96-3
- Formula:C10H14O2
- Molecular Weight:166.22
IUPAC Name: (1S,6S)-6-methyl-3-(propan-2-ylidene)-7-oxabicyclo[4.1.0]heptan-2-one
InChIKey: AKASWINDKIEEBO-ZJUUUORDSA-N
SMILES: O=C1[C@@]2([H])O[C@@]2(C)CC/C1=C(C)/C
Biological Activity: Piperitenone oxide is an orally active monoterpene ketone. Piperitenone oxide can be isolated from the essential oils of plants belonging to Mentha x villosa and Ziziphora clinopodioides. Piperitenone oxide induces differentiation. Piperitenone oxide induces chromosome breakage damage, aneuploidy damage and DNA single-strand breaks. Piperitenone oxide reduces ET-1 levels. Piperitenone oxide exerts antihypertensive effects. Piperitenone oxide can be used in studies related to colon cancer[1][2][3].
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Piperitenone oxide | Piperitenone oxide is an orally active monoterpene ketone. Piperitenone oxide can be isolated from the essential oils of plants belonging to Mentha x villosa and Ziziphora clinopodioides. Piperitenone oxide induces differentiation. Piperitenone oxide induces chromosome breakage damage, aneuploidy damage and DNA single-strand breaks. Piperitenone oxide reduces ET-1 levels. Piperitenone oxide exerts antihypertensive effects. Piperitenone oxide can be used in studies related to colon cancer. | |||||||||||||||||||||
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References
- [1]. Nakamura Y, et al. Differentiation-inducing effect of piperitenone oxide, a fragrant ingredient of spearmint (Mentha spicata), but not carvone and menthol, against human colon cancer cells[J]. journal of functional foods, 2014, 8: 62-67.
- [2]. Di Sotto A, et al. Genotoxicity assessment of piperitenone oxide: An in vitro and in silico evaluation. Food Chem Toxicol. 2017;106(Pt A):506-513. [Content Brief]
- [3]. Lan W, et al. Antihypertensive effect of piperitenone oxide on spontaneously hypertensive rat by regulating calcium balance and reducing endothelin-1 secretion[J]. Bangladesh Journal of Pharmacology, 2017, 12(3): 341-347.
