36052-37-6
36052-37-6
Chemical Structure
Alpinetin
- CAS No.: 36052-37-6
- Formula:C16H14O4
- Molecular Weight:270.28
IUPAC Name: (S)-7-hydroxy-5-methoxy-2-phenylchroman-4-one
InChIKey: QQQCWVDPMPFUGF-ZDUSSCGKSA-N
SMILES: O=C1C[C@@H](C2=CC=CC=C2)OC3=CC(O)=CC(OC)=C13
Biological Activity: Alpinetin is a flavonoid isolated from cardamom and possesses antitumor, antiinflammation, hepatoprotective, cardiovascular protective, lung protective, antibacterial, antiviral, neuroprotective properties. Alpinetin inhibits lipopolysaccharide (LPS)-induced inflammation, activates PPAR-γ, activates Nrf2, and inhibits TLR4 expression to protect LPS-induced renal injury[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Alpinetin | 99.65% | Alpinetin is a flavonoid isolated from cardamom and possesses antitumor, antiinflammation, hepatoprotective, cardiovascular protective, lung protective, antibacterial, antiviral, neuroprotective properties. Alpinetin inhibits lipopolysaccharide (LPS)-induced inflammation, activates PPAR-γ, activates Nrf2, and inhibits TLR4 expression to protect LPS-induced renal injury. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Hu K, et al. Alpinetin inhibits LPS-induced inflammatory mediator response by activating PPAR-γ in THP-1-derived macrophages. Eur J Pharmacol. 2013 Dec 5;721(1-3):96-102. [Content Brief]
- [2]. Zhao G, et al. Alpinetin: A Review of Its Pharmacology and Pharmacokinetics. Front Pharmacol. 2022 Feb 4;13:814370. [Content Brief]
- [3]. Gul S, et al. Alpinetin: a Dietary Flavonoid with Diverse Anticancer Effects. Appl Biochem Biotechnol. 2022 Sep;194(9):4220-4243. [Content Brief]
- [4]. Liang Y, et al. Alpinetin ameliorates inflammatory response in LPS-induced endometritis in mice. Int Immunopharmacol. 2018 Sep;62:309-312. [Content Brief]
