37517-30-9
37517-30-9
Chemical Structure
Acebutolol
- CAS No.: 37517-30-9
- Formula:C18H28N2O4
- Molecular Weight:336.43
IUPAC Name: N-(3-acetyl-4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)butyramide
InChIKey: GOEMGAFJFRBGGG-UHFFFAOYSA-N
SMILES: CCCC(NC1=CC=C(OCC(O)CNC(C)C)C(C(C)=O)=C1)=O
Biological Activity: Acebutolol is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol is used for hypertension, angina pectoris and cardiac arrhythmias research[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Acebutolol | 99.70% | Acebutolol is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol is used for hypertension, angina pectoris and cardiac arrhythmias research. | ||||||||||||||||||||
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Acebutolol-d7 | Acebutolol-d7 is a deuterium labeled Acebutolol. Acebutolol is a selective β1 adrenergic receptor antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias. | |||||||||||||||||||||
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References
- [1]. Piquette-Miller, M. and F. Jamali, Pharmacokinetics and multiple peaking of acebutolol enantiomers in rats. Biopharm Drug Dispos, 1997. 18(6): p. 543-56. [Content Brief]
- [2]. Bristow MR, et al. Treatment of chronic heart failure with β-adrenergic receptor antagonists: a convergence of receptor pharmacology and clinical cardiology. Circ Res. 2011 Oct 28;109(10):1176-94. [Content Brief]
- [3]. Mostafavi, S., R. Lewanczuk, and R. Foster, Influence of acebutolol and metoprolol on cardiac output and regional blood flow in rats. Biopharm Drug Dispos, 2000. 21(4): p. 121-8. [Content Brief]
Keywords
