398515-96-3
Chemical Structure
III-31-C
- CAS No.: 398515-96-3
- Formula:C35H52N4O7
- Molecular Weight:640.81
IUPAC Name: methyl (benzyl((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutyl)carbamoyl)-L-leucyl-L-valinate
InChIKey: DINAVFJXFRFCRE-ZXYZSCNASA-N
SMILES: O=C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(OC)=O)=O)N(C[C@@H](O)[C@@H](NC(OC(C)(C)C)=O)CC1=CC=CC=C1)CC2=CC=CC=C2
Biological Activity: III-31-C is a (hydroxyethyl)urea γ-secretase inhibitor. III-31-C inhibits Aऔ production with an IC50 of 10 nM in the cell-free γ-secretase assay and 200 nM in APP-transfected cells. III-31-C can be used in Alzheimer's disease research[1].
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III-31-C | III-31-C is a (hydroxyethyl)urea γ-secretase inhibitor. III-31-C inhibits Aऔ production with an IC50 of 10 nM in the cell-free γ-secretase assay and 200 nM in APP-transfected cells. III-31-C can be used in Alzheimer's disease research. | |||||||||||||||||||||
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Keywords
