413605-11-5
413605-11-5
Chemical Structure
LP-471756
- CAS No.: 413605-11-5
- Formula:C19H23NO2S
- Molecular Weight:329.46
IUPAC Name: 4-cyclohexyl-N-(o-tolyl)benzenesulfonamide
InChIKey: STLMNZVBCJVQOZ-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(C=C1)C2CCCCC2)(NC3=CC=CC=C3C)=O
Biological Activity: LP-471756 is a potent GPR139 antagonist with an IC50 value of 640 nM. LP-471756 inhibits LP-360924-stimulated cAMP production[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LP-471756 | 99.53% | LP-471756 is a potent GPR139 antagonist with an IC50 value of 640 nM. LP-471756 inhibits LP-360924-stimulated cAMP production. | ||||||||||||||||||||
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References
- [1]. Vedel L, et al. Pharmacology and function of the orphan GPR139 G protein-coupled receptor. Basic Clin Pharmacol Toxicol. 2020 Jun;126 Suppl 6(Suppl 6):35-46. [Content Brief]
- [2]. Hu LA, et al. Identification of surrogate agonists and antagonists for orphan G-protein-coupled receptor GPR139. J Biomol Screen. 2009 Aug;14(7):789-97. [Content Brief]
Keywords
