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ELN484228 

Cat. No.: HY-115038 Purity: 99.77%
Handling Instructions

ELN484228 is a blocker of α-synuclein which is a key protein in Parkinson’s disease.

For research use only. We do not sell to patients.

ELN484228 Chemical Structure

ELN484228 Chemical Structure

CAS No. : 312-63-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 77 In-stock
Estimated Time of Arrival: December 31
5 mg USD 70 In-stock
Estimated Time of Arrival: December 31
10 mg USD 95 In-stock
Estimated Time of Arrival: December 31
25 mg USD 195 In-stock
Estimated Time of Arrival: December 31
50 mg USD 295 In-stock
Estimated Time of Arrival: December 31
100 mg USD 520 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

ELN484228 is a blocker of α-synuclein which is a key protein in Parkinson’s disease.

IC50 & Target

α-synuclein[1]

Molecular Weight

251.28

Formula

C₁₂H₁₀FNO₂S

CAS No.

312-63-0

SMILES

O=S(C1=CC=CC=C1)(NC2=CC=C(F)C=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (198.98 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9796 mL 19.8981 mL 39.7962 mL
5 mM 0.7959 mL 3.9796 mL 7.9592 mL
10 mM 0.3980 mL 1.9898 mL 3.9796 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (9.95 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (9.95 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (9.95 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
ELN484228
Cat. No.:
HY-115038
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