41964-07-2
Chemical Structure
Tolimidone
Synonym(s): MLR-1023
- CAS No.: 41964-07-2
- Formula:C11H10N2O2
- Molecular Weight:202.21
IUPAC Name: 5-(m-tolyloxy)pyrimidin-2(1H)-one
InChIKey: HJQILFPVRNHTIG-UHFFFAOYSA-N
SMILES: O=C1N=CC(OC2=CC=CC(C)=C2)=CN1
Biological Activity: Tolimidone is a potent and selective allosteric activator of Lyn kinase with an EC50 of 63 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tolimidone | 99.98% | Tolimidone is a potent and selective allosteric activator of Lyn kinase with an EC50 of 63 nM. | ||||||||||||||||||||
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Jineol | 99.68% | Jineol is a cytotoxic alkaloid from the centipede Scolopendra subspinipes. Jineol exhibits modest cytotoxic activity in vitro against the growth of human tumor cell lines. | ||||||||||||||||||||
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4,4'-Oxydiphenol | 4,4'-Oxydiphenol (4,4'-Dihydroxydiphenyl ether) is an inhibitor of estrogen receptor (IC50 = 60 μM ) . | |||||||||||||||||||||
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3-Methylquinoline | 98.86% | 3-Methylquinoline is a selective cytochrome P450 (CYP1A2) inhibitor with an IC50 of 13 μM. 3-Methylquinoline can reduce the metabolic clearance of CYP1A2 substrate drugs. 3-Methylquinoline can inhibit the activation of carcinogenic precursors. | ||||||||||||||||||||
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6-Methoxyquinoline | 99.71% | 6-Methoxyquinoline consists of a quinoline ring system with a methoxy group attached to the sixth carbon atom. This compound occurs naturally in certain plants, such as tobacco and tea, and has been shown to have biological activities, including antioxidant, anti-inflammatory and antitumor properties. Furthermore, 6-Methoxyquinoline can be used as a building block for the synthesis of other organic compounds, especially those with potential pharmaceutical applications. Due to its ability to bind nucleic acids and proteins, it can also be used as a fluorescent probe in biochemical and biomedical research. | ||||||||||||||||||||
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8-Methoxyquinoline | 8-Methoxyquinoline is a structural analogue of 8-hydroxyquinoline (HY-B1005). 8-Methoxyquinoline does not bind copper. 8-Methoxyquinoline could neither inhibit the chymotrypsin-like activity of the proteasome in breast cancer cell cultures nor induce cancer cell death. 8-Methoxyquinoline can be used in the research of breast cancer. |
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3-Phenoxyphenol | 3-Phenoxyphenol is a polymeric Phenol. 3-Phenoxyphenol generates iodinated and chlorinated polymeric phenolic disinfection byproducts during chlorination disinfection. | |||||||||||||||||||||
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2-Hydroxy-4-methylquinoline | 2-Hydroxy-4-methylquinoline is a synthetic intermediate. 2-Hydroxy-4-methylquinoline is formed via cyclization of acetoacetanilide under the action of concentrated sulfuric acid through the Conrad-Limpach-Knorr synthesis. 2-Hydroxy-4-methylquinoline can be used in studies related to the synthesis of chemotherapeutic agents. | |||||||||||||||||||||
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4,4'-Oxydipyridine | 4,4'-Oxydipyridine is a metal-organic framework (MOF). | |||||||||||||||||||||
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Tyrosinase-IN-29 | Tyrosinase-IN-29 (compound 5c) is a potent inhibitor of tyrosinase abTYR (IC50: 6.11 μM). Tyrosinase-IN-29 can be used to further study the inhibition of skin hyperpigmentation. | |||||||||||||||||||||
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3-Phenoxybenzaldehyde | 99.6% | 3-Phenoxybenzaldehyde (m-Phenoxybenzaldehyde) is the major product of CYP6AA3-mediated deltamethrin metabolism, generated by oxidative cleavage of deltamethrin. 3-Phenoxybenzaldehyde often serves as an intermediate. | ||||||||||||||||||||
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