425399-05-9
425399-05-9
Chemical Structure
CASIN
- CAS 番号: 425399-05-9
- Formula:C20H22N2O
- Molecular Weight:306.40
IUPAC Name: 2-((6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)amino)ethan-1-ol
InChIKey: RXIUMAOXORBRCY-UHFFFAOYSA-N
SMILES: OCCNC1C(NC2=C3C=C(C4=CC=CC=C4)C=C2)=C3CCC1
Biological Activity: CASIN is a selective GTPase Cdc42 inhibitor with an IC50 of 2 uM. CASIN can be used for the research of cancer[1][2].
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CASIN | 99.89% | CASIN is a selective GTPase Cdc42 inhibitor with an IC50 of 2 uM. CASIN can be used for the research of cancer. | ||||||||||||||||||||
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References
- [1]. Florian MC et al. Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell, 2012 May 4, 10(5):520-30. [Content Brief]
- [2]. Nguyen P, et al. Rational Targeting of Cdc42 Overcomes Drug Resistance of Multiple Myeloma. Front Oncol. 2019 Oct 1;9:958. doi: 10.3389/fonc.2019.00958. [Content Brief]
