442-52-4
442-52-4
Chemical Structure
Clemizole
- CAS No.: 442-52-4
- Formula:C19H20ClN3
- Molecular Weight:325.84
IUPAC Name: 1-(4-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzo[d]imidazole
InChIKey: CJXAEXPPLWQRFR-UHFFFAOYSA-N
SMILES: ClC1=CC=C(C=C1)CN2C(CN3CCCC3)=NC4=CC=CC=C24
Biological Activity: Clemizole is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. Clemizole is an inhibitor of TRPC5 channel. The IC50 of Clemizole for RNA binding by NS4B is 24±1 nM, whereas its EC50 for viral replication is 8 µM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Clemizole | 98.42% | Clemizole is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. Clemizole is an inhibitor of TRPC5 channel. The IC50 of Clemizole for RNA binding by NS4B is 24±1 nM, whereas its EC50 for viral replication is 8 µM. | ||||||||||||||||||||
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Clemizole-d4 | 99.82% | Clemizole-d4 is a deuterium labeled Clemizole. Clemizole is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. | ||||||||||||||||||||
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Keywords
