442898-75-1
442898-75-1
Chemical Structure
HSP90-IN-22
- CAS No.: 442898-75-1
- Formula:C25H30N4O3
- Molecular Weight:434.53
IUPAC Name: N-(2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl)-3,4-dimethoxybenzamide
InChIKey: YGHVMEYBSUHIGF-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C(OC)=C1)OC)NC2=CC3=C(N=C(N4CCN(CC4)CC)C=C3C)C=C2
Biological Activity: HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor with antiproliferative properties on cells with IC50 values of 3.65 μM for MCF7 breast cancer cells and 2.71 μM for SKBr3 breast cancer cells, respectively.
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HSP90-IN-22 | 98.0% | HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor with antiproliferative properties on cells with IC50 values of 3.65 μM for MCF7 breast cancer cells and 2.71 μM for SKBr3 breast cancer cells, respectively. | ||||||||||||||||||||
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Keywords
