462-88-4
462-88-4
Chemical Structure
Ureidopropionic acid
Synonym(s): 3-Ureidopropionic acid
- CAS No.: 462-88-4
- Formula:C4H8N2O3
- Molecular Weight:132.12
IUPAC Name: 3-ureidopropanoic acid
InChIKey: JSJWCHRYRHKBBW-UHFFFAOYSA-N
SMILES: O=C(O)CCNC(N)=O
Biological Activity: Ureidopropionic acid (3-Ureidopropionic acid) is a selective mitochondrial respiratory chain complex V inhibitor. Ureidopropionic acid induces the production of reactive oxygen species, delayed elevation of intracellular calcium concentration, secondary energy-dependent excitotoxicity and neurodegeneration in neurons. Ureidopropionic acid promotes neuropathological changes by impairing mitochondrial energy metabolism, oxidative stress and excitotoxicity pathways. Ureidopropionic acid can be used in studies related to 3-ureidopropionase deficiency and severe propionic aciduria[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ureidopropionic acid | 99.95% | Ureidopropionic acid (3-Ureidopropionic acid) is a selective mitochondrial respiratory chain complex V inhibitor. Ureidopropionic acid induces the production of reactive oxygen species, delayed elevation of intracellular calcium concentration, secondary energy-dependent excitotoxicity and neurodegeneration in neurons. Ureidopropionic acid promotes neuropathological changes by impairing mitochondrial energy metabolism, oxidative stress and excitotoxicity pathways. Ureidopropionic acid can be used in studies related to 3-ureidopropionase deficiency and severe propionic aciduria. | ||||||||||||||||||||
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Ureidopropionic acid (Standard) | 99.96% | Ureidopropionic acid (Standard) is the analytical standard of Ureidopropionic acid. This product is intended for research and analytical applications. Ureidopropionic acid (3-Ureidopropionic acid) is a selective mitochondrial respiratory chain complex V inhibitor. Ureidopropionic acid induces the production of reactive oxygen species, delayed elevation of intracellular calcium concentration, secondary energy-dependent excitotoxicity and neurodegeneration in neurons. Ureidopropionic acid promotes neuropathological changes by impairing mitochondrial energy metabolism, oxidative stress and excitotoxicity pathways. Ureidopropionic acid can be used in studies related to 3-ureidopropionase deficiency and severe propionic aciduria. | ||||||||||||||||||||
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4-Acetamidobutanoic acid (Standard) | 99.23% | 4-Acetamidobutanoic acid (Standard) (N-acetyl GABA (Standard)) is the analytical standard of 4-Acetamidobutanoic acid (HY-101411). This product is intended for research and analytical applications. 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities. | ||||||||||||||||||||
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(R)-Ureidoisobutyric acid | (R)-Ureidoisobutyric acid is a nucleoside metabolite. | |||||||||||||||||||||
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4-Guanidinobutanoic acid (Standard) | ≥98% | 4-Guanidinobutanoic acid (Standard) is the analytical standard of 4-Guanidinobutanoic acid (HY-113286). This product is intended for research and analytical applications. 4-Guanidinobutanoic acid is a metabolite of arginine and an orally active SLC36A1/Hedgehog signaling pathway activator. 4-Guanidinobutanoic acid drives epithelial reprogramming, enhances intestinal stem cell function and goblet cell differentiation. 4-Guanidinobutanoic acid promotes the enrichment of Akkermansia muciniphila via mucus-dependent niche expansion, regulates intestinal homeostasis, and establishes a microbiota-host feedback loop. 4-Guanidinobutanoic acid exhibits anti-aging and healthspan-regulating properties. 4-Guanidinobutanoic acid can be used in research related to ulcerative colitis, amyotrophic lateral sclerosis, and Duchenne muscular dystrophy. | ||||||||||||||||||||
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N-Bromoacetyl-β-alanine | N-Bromoacetyl-β-alanine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. N-Bromoacetyl-β-alanine is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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H-D-Ala-β-Ala-OH | H-D-Ala-β-Ala-OH is a synthetic alanyl dipeptide with no activity against Bacillus thiaminolyticus spore germination and no antibacterial activity against gram-positive and gram-negative bacteria at 100 μg/mL. | |||||||||||||||||||||
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Ac-β-Ala-OH | 98.0% | Ac-β-Ala-OH is an abnormal amino acid metabolite and also serves as a mono-N-protected amino acid (MPAA) ligand. Ac-β-Ala-OH supports the β-C (sp3)-H arylation of aliphatic carboxylic acids and also serves as a starting building block for the reverse MAP core in the construction of the gonorrhea vaccine candidate TMCP2. | ||||||||||||||||||||
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Glycylglycine | 99.90% | Glycylglycine is a non-selective glycylglycine dipeptidase substrate and iNOS inhibitor. Glycylglycine can cross the cell membrane by passive diffusion and is hydrolyzed to glycine in the cell, participating in energy metabolism and antioxidant processes. Glycylglycine promotes spermatogonial stem cells (SSCs) proliferation, inhibits astrocyte overactivation and reduces nitric oxide (NO) release, while upregulating the expression of neurotrophic factors (such as PDGFA, FGF2, CNTF) to support nerve myelin repair. Glycylglycine can be used to study male reproductive biology (such as SSCs proliferation regulation) and neurodegenerative diseases (such as neuroprotective mechanisms in multiple sclerosis). | ||||||||||||||||||||
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N-β-Alanyl-β-alanine | 99.82% | N-β-Alanyl-β-alanine (NSC 97926) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development. | ||||||||||||||||||||
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Ompenaclid (Standard) | ≥98% | Ompenaclid (RGX-202) is an oral small-molecule SLC6A8 transporter inhibitor. Ompenaclid robustly inhibits creatine import in vitro and in vivo, reduces intracellular phosphocreatine and ATP levels, and induces tumor apoptosis. Ompenaclid can be used for the research of cancer and duchenne muscular dystrophy. | ||||||||||||||||||||
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Succinamic acid | Succinamic acid is a weak inhibitor for human LL-xylose reductase with an IC50 of 1.45 mM. Succinamic acid can be used as a linker for synthesis of CQ-16 (HY-169336). | |||||||||||||||||||||
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