468-36-0
468-36-0
Chemical Structure
Isoconessimine
- CAS No.: 468-36-0
- Formula:C23H38N2
- Molecular Weight:342.56
InChIKey: UBWOPONWVXRTKE-ALCLCTQTSA-N
SMILES: C[C@H]1[C@]2([H])[C@]3(CN1C)[C@](CC2)([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)NC)=CC4)C)([H])CC3
Biological Activity: Isoconessimine is a steroidal alkaloid that can be found in the seeds of Holarrhena antidysenterica, and the IC50 value of its acetylcholinesterase inhibitory activity is > 300 μM[1][2].
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Isoconessimine | Isoconessimine is a steroidal alkaloid that can be found in the seeds of Holarrhena antidysenterica, and the IC50 value of its acetylcholinesterase inhibitory activity is > 300 μM. | |||||||||||||||||||||
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References
- [1]. Zhou LN, et al. Antibacterial steroidal alkaloids from Holarrhena antidysenteriaca. Chin J Nat Med. 2017;15(7):540-545. [Content Brief]
- [2]. Yang ZD, et al. Steroidal alkaloids from Holarrhena antidysenterica as acetylcholinesterase inhibitors and the investigation for structure-activity relationships. Life Sci. 2012;90(23-24):929-933. [Content Brief]
Keywords
