Isoconessimine
Isoconessimine is a steroidal alkaloid that can be found in the seeds of Holarrhena antidysenterica.
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- CAS No.: 468-36-0
- Formule: C23H38N2
- Masse moléculaire:342.56
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
Isoconessimine (24 h) exhibits no detectable intrinsic antibacterial activity against methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA)[1].
Isoconessimine (0.1 mg/mL; 20 min) exhibits very weak inhibitory activity against purified acetylcholinesterase, with an IC50 value > 300 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 468-36-0
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Masse moléculaire 342.56
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Formule C23H38N2
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SMILES
C[C@H]1[C@]2([H])[C@]3(CN1C)[C@](CC2)([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)NC)=CC4)C)([H])CC3
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Zhou LN, et al. Antibacterial steroidal alkaloids from Holarrhena antidysenteriaca. Chin J Nat Med. 2017;15(7):540-545. [Content Brief]
[2]. Yang ZD, et al. Steroidal alkaloids from Holarrhena antidysenterica as acetylcholinesterase inhibitors and the investigation for structure-activity relationships. Life Sci. 2012;90(23-24):929-933. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)