Isoconessimine TFA
Based on 1 Customer Validation
Isoconessimine TFA is a steroidal alkaloid that can be found in the seeds of Holarrhena antidysenterica, and the IC50 value of its acetylcholinesterase inhibitory activity is > 300 μM.
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- Formule: C25H39F3N2O2
- Masse moléculaire:456.58
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Stockage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Isoconessimine (24 h) TFA exhibits no detectable intrinsic antibacterial activity against methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA)[1].
Isoconessimine (0.1 mg/mL; 20 min) TFA exhibits very weak inhibitory activity against purified acetylcholinesterase, with an IC50 value > 300 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Masse moléculaire 456.58
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Formule C25H39F3N2O2
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SMILES
OC(C(F)(F)F)=O.C[C@H]1[C@]2([H])[C@]3(CN1C)[C@](CC2)([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)NC)=CC4)C)([H])CC3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Pureté et documentation
Références
[1]. Zhou LN, et al. Antibacterial steroidal alkaloids from Holarrhena antidysenteriaca. Chin J Nat Med. 2017;15(7):540-545. [Content Brief]
[2]. Yang ZD, et al. Steroidal alkaloids from Holarrhena antidysenterica as acetylcholinesterase inhibitors and the investigation for structure-activity relationships. Life Sci. 2012;90(23-24):929-933. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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