480-33-1
Chemical Structure
Mellein
Synonym(s): (R)-Mellein
- No. CAS: 480-33-1
- Formula:C10H10O3
- Molecular Weight:178.18
IUPAC Name: (R)-8-hydroxy-3-methylisochroman-1-one
InChIKey: KWILGNNWGSNMPA-ZCFIWIBFSA-N
SMILES: O=C1C2=C(O)C=CC=C2C[C@@H](C)O1
Biological Activity: Mellein ((R)-Mellein) is an isocoumarin compound with antibacterial activity. Mellein inhibits the activity of HCV Protease, disrupts the cell wall of Xanthomonas sp., and acts as an insect trail pheromone. Mellein is applicable to research related to fungal infections, bacterial infections, and hepatitis C virus infections[1][2][3][4].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Mellein | 98.54% | Mellein ((R)-Mellein) is an isocoumarin compound with antibacterial activity. Mellein inhibits the activity of HCV Protease, disrupts the cell wall of Xanthomonas sp., and acts as an insect trail pheromone. Mellein is applicable to research related to fungal infections, bacterial infections, and hepatitis C virus infections. | ||||||||||||||||||||
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- [1]. Sun H, et al. Synthesis of (R)-mellein by a partially reducing iterative polyketide synthase. Journal of the American Chemical Society. 2012 Jul 25;134(29):11924-7. [Content Brief]
- [2]. Moore JH, et al. Mellein and 4-Hydroxymellein Production by Aspergillus ochraceus Wilhelm. Applied Microbiology. 1972 Jun;23(6):1067-1072.
- [3]. Saraswathi M, et al. Isolation, purification and structural elucidation of Mellein from endophytic fungus Lasiodiplodia theobromae strain (SJF-1) and its broad-spectrum antimicrobial and pharmacological properties. Letters in applied microbiology. 2022 Dec;75(6):1475-1485. [Content Brief]
- [4]. Mitaka Y, et al. A termite fungistatic compound, mellein, inhibits entomopathogenic fungi but not egg-mimicking termite ball fungi. Applied Entomology and Zoology. 2019;54:39-46.
Keywords