4871-40-3
4871-40-3
Chemical Structure
MAC13772
- CAS No.: 4871-40-3
- Formula:C8H9N3O3S
- Molecular Weight:227.24
IUPAC Name: 2-((2-nitrophenyl)thio)acetohydrazide
InChIKey: CZXFCCXLFQCYBK-UHFFFAOYSA-N
SMILES: O=C(NN)CSC1=CC=CC=C1[N+]([O-])=O
Biological Activity: MAC13772 is a BioA inhibitor with an IC50 of 0.28 μM against E. coli and an IC50 of 0.269 μM against A. baumannii. MAC13772 inhibits bacterial growth by targeting the biotin biosynthesis pathway. MAC13772 can be used in studies related to bacterial infections[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MAC13772 | 99.33% | MAC13772 is a BioA inhibitor with an IC50 of 0.28 μM against E. coli and an IC50 of 0.269 μM against A. baumannii. MAC13772 inhibits bacterial growth by targeting the biotin biosynthesis pathway. MAC13772 can be used in studies related to bacterial infections. | ||||||||||||||||||||
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References
- [1]. Sinha K. Design and Synthesis of Acetohydrazide Derivatives: Enhancing Potency and Stability against Gram-negative Pathogens. Université d'Ottawa| University of Ottawa, 2024.
- [2]. Zhang J, et al. Decreasing protein biotinylation background in a diatom facilitates proximity labeling of the periplastidial compartment proteome. Plant J. 2025;122(5):e70259. [Content Brief]
Keywords
