4871-40-3
4871-40-3
Chemical Structure
MAC13772
- CAS No.: 4871-40-3
- Formula:C8H9N3O3S
- Molecular Weight:227.24
IUPAC Name: 2-((2-nitrophenyl)thio)acetohydrazide
InChIKey: CZXFCCXLFQCYBK-UHFFFAOYSA-N
SMILES: O=C(NN)CSC1=CC=CC=C1[N+]([O-])=O
Biological Activity: MAC13772 is a BioA inhibitor with an IC50 of 0.28 μM against E. coli and an IC50 of 0.269 μM against A. baumannii. MAC13772 inhibits bacterial growth by targeting the biotin biosynthesis pathway. MAC13772 can be used in studies related to bacterial infections[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MAC13772 | 99.33% | MAC13772 is a BioA inhibitor with an IC50 of 0.28 μM against E. coli and an IC50 of 0.269 μM against A. baumannii. MAC13772 inhibits bacterial growth by targeting the biotin biosynthesis pathway. MAC13772 can be used in studies related to bacterial infections. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.78
HY-W0276542-Nitrobenzamide -
Similarity Score 0.77
HY-133706S2-Nitrobenzaldehyde semicarbazone-13C,15N2 -
Similarity Score 0.77
HY-1385382-Nitrobenzaldehyde Semicarbazone -
Similarity Score 0.77
HY-138538S2-Nitrobenzaldehyde semicarbazone-13C,15N2-1 -
Similarity Score 0.75
HY-Y08912-Nitrobenzoic acid -
Similarity Score 0.75
HY-Z0007R2-Chloro-N-(4-nitrophenyl)acetamide (Standard) -
Similarity Score 0.74
HY-W0080962-Nitrobenzenesulfonamide -
Similarity Score 0.74
HY-133689AS3-Nitrophenylhydrazine-13C6 hydrochloride -
Similarity Score 0.74
HY-W053641(E)-2-Nitrocinnamic acid -
Explore the MedChemAI to find more analogs
References
- [1]. Sinha K. Design and Synthesis of Acetohydrazide Derivatives: Enhancing Potency and Stability against Gram-negative Pathogens. Université d'Ottawa| University of Ottawa, 2024.
- [2]. Zhang J, et al. Decreasing protein biotinylation background in a diatom facilitates proximity labeling of the periplastidial compartment proteome. Plant J. 2025;122(5):e70259. [Content Brief]
