498-96-4
498-96-4
Chemical Structure
Guvacine
- CAS No.: 498-96-4
- Formula:C6H9NO2
- Molecular Weight:127.14
IUPAC Name: 1,2,5,6-tetrahydropyridine-3-carboxylic acid
InChIKey: QTDZOWFRBNTPQR-UHFFFAOYSA-N
SMILES: O=C(C1=CCCNC1)O
Biological Activity: Guvacine, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively[1].
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Guvacine | Guvacine, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively. | |||||||||||||||||||||
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References
Keywords
