50-34-0
50-34-0
Chemical Structure
Propantheline bromide
- CAS No.: 50-34-0
- Formula:C23H30BrNO3
- Molecular Weight:448.39
IUPAC Name: N-(2-((9H-xanthene-9-carbonyl)oxy)ethyl)-N-isopropyl-N-methylpropan-2-aminium bromide
InChIKey: XLBIBBZXLMYSFF-UHFFFAOYSA-M
SMILES: CC([N+](C(C)C)(C)CCOC(C1C2=C(OC3=C1C=CC=C3)C=CC=C2)=O)C.[Br-]
Biological Activity: Propantheline bromide is an orally active mAChR antagonist. Propantheline bromide can be used in the research of smooth muscle dysfunction, excessive sweating, cramps or spasms of the stomach, intestines or bladder, and involuntary urination. Propantheline bromide can hardly cross the blood-brain barrier[1][2][3][4].
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Propantheline bromide | 97.38% | Propantheline bromide is an orally active mAChR antagonist. Propantheline bromide can be used in the research of smooth muscle dysfunction, excessive sweating, cramps or spasms of the stomach, intestines or bladder, and involuntary urination. Propantheline bromide can hardly cross the blood-brain barrier. | ||||||||||||||||||||
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Propantheline bromide (Standard) | ≥98% | Propantheline (bromide) (Standard) is the analytical standard of Propantheline (bromide). This product is intended for research and analytical applications. Propantheline bromide is an orally active mAChR antagonist. Propantheline bromide can be used in the research of smooth muscle dysfunction, excessive sweating, cramps or spasms of the stomach, intestines or bladder, and involuntary urination. | ||||||||||||||||||||
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Propantheline-d3 bromide | 99.00% | Propantheline-d3 (bromide) is the deuterium labeled Propantheline bromide. Propantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis. | ||||||||||||||||||||
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References
- [1]. J Mokry, et al. Propantheline and in vitro reactivity of urinary bladder smooth muscle in guinea pigs. Bratisl Lek Listy. 2005;106(4-5):151-4. [Content Brief]
- [2]. Richard Jewell, et al. Propantheline. xPharm: The Comprehensive Pharmacology Reference. 2007, Pages 1-5.
- [3]. S Kobayashi, et al. Effects of YM905, a novel muscarinic M3-receptor antagonist, on experimental models of bowel dysfunction in vivo. Jpn J Pharmacol. 2001 Jul;86(3):281-8. [Content Brief]
