500-49-2
500-49-2
Chemical Structure
Divarin
Synonym(s): 5-Propylbenzene-1,3-diol
- CAS No.: 500-49-2
- Formula:C9H12O2
- Molecular Weight:152.19
IUPAC Name: 5-propylbenzene-1,3-diol
InChIKey: FRNQLQRBNSSJBK-UHFFFAOYSA-N
SMILES: OC1=CC(CCC)=CC(O)=C1
Biological Activity: Divarin (5-Propylbenzene-1,3-diol) is an important precursor and intermediate in the synthesis of cannabinoids, and is present in certain bacteria and lichens. Divarin exhibits antioxidant activity. Divarin acts as an electron acceptor to directly scavenge superoxide anions and modulates the transcription of oxidative stress genes such as soxS, thereby enhancing bacterial resistance to late-stage reactive oxygen species (ROS) through a non-enzymatic mechanism. Divarin can be used in research on antioxidant development[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Divarin | 99.35% | Divarin (5-Propylbenzene-1,3-diol) is an important precursor and intermediate in the synthesis of cannabinoids, and is present in certain bacteria and lichens. Divarin exhibits antioxidant activity. Divarin acts as an electron acceptor to directly scavenge superoxide anions and modulates the transcription of oxidative stress genes such as soxS, thereby enhancing bacterial resistance to late-stage reactive oxygen species (ROS) through a non-enzymatic mechanism. Divarin can be used in research on antioxidant development. | ||||||||||||||||||||
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4-Butylresorcinol (Standard) | ≥98% | 4-Butylresorcinol (Standard) is the analytical standard of 4-Butylresorcinol. This product is intended for research and analytical applications. 4-Butylresorcinol is a phenol derivative which can inhibit tyrosinase with IC50 of 11.27 μM. | ||||||||||||||||||||
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Orcinol | 99.97% | Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases. | ||||||||||||||||||||
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Olivetol (Standard) | ≥98% | Olivetol (Standard) is the analytical standard of Olivetol. This product is intended for research and analytical applications. Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2. Olivetol also inhibits CYP2C19 and CYP2D6 activity, with IC50s of 15.3 μM, 7.21 μM and Kis of 2.71 μM, 2.87 μM, respectively. | ||||||||||||||||||||
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5-Methylresorcinol monohydrate | 99.81% | 5-Methylresorcinol monohydrate (Orcinol monohydrate) is a tyrosinase inhibitor. 5-Methylresorcinol monohydrate shows cytotoxicity. 5-Methylresorcinol monohydrate also is an oral active and cross the blood-brain barrier anxiolytic agent. | ||||||||||||||||||||
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3-N-Propylphenol | 98.49% | 3-N-Propylphenol is a small phenolic derivative containing a hydroxyl aryl group that competitively inhibits the binding of the peptide to pancreatic-specific protein disulfide isomerase (PDIp). 3-Propylphenol can be used for research on pancreatic-related diseases. | ||||||||||||||||||||
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4-Propylphenol | 99.80% | 4-Propylphenol is a plant-derived phenolic compound. 4-Propylphenol causes an increase in ROS within the Fusarium graminearum cells, leading to damage to the DNA and cell membranes of the mycelia, effectively inhibiting the growth of the mycelia. 4-Propylphenol also has a growth inhibitory effect on walnut pathogenic fungi (C. gloeosporioides, C. siamense, A. alternata), with its EC50 ranging from 29.11 to 31.89 mg/L, and it also inhibits spore germination, with EC50 being 55.04-71.85 mg/L. 4-Propylphenol can be used in the research of fungal diseases in walnuts and wheat Fusarium head blight. | ||||||||||||||||||||
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3,5-Dihydroxyacetophenone | 99.96% | 3,5-Dihydroxyacetophenone is a drug intermediate that can be used in the synthesis of the active stilbene dimer dehydro-δ-viniferin. | ||||||||||||||||||||
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4-Propylcatechol | 99.74% | 4-Propylcatechol is an Allylpyrocatechol (HY-124127) analog. 4-Propylcatechol shows anti-malarial activity against Plasmodium falciparum CDC-1 with an IC50 of 32 µM. | ||||||||||||||||||||
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5-Heptylresorcinol | 5-Heptylresorcinol is a precursor in the synthesis of cannabidiphorol. | |||||||||||||||||||||
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4-Ethylcatechol (Standard) | ≥98% | 4-Ethylcatechol is a ring-dihydroxylated metabolite of 4-Ethylphenol that leads to oxidative DNA damage. | ||||||||||||||||||||
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References
- [1]. Bátkai S, et al. Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors. British journal of pharmacology. 2012 Apr;165(8):2450-61. [Content Brief]
- [2]. Gryazeva IV, et al. Evaluation of the potential of alkylresorcinols as superoxide anion scavengers and sox-regulon modulators using nitroblue tetrazolium and bioluminescent cell-based assays. Cellular & molecular biology letters. 2015 Mar;20(1):24-37.
