501-26-8
Chemical Structure
Cardanol monoene
Synonym(s): Cardanol C15:1
- CAS No.: 501-26-8
- Formula:C21H34O
- Molecular Weight:302.49
IUPAC Name: (Z)-3-(pentadec-8-en-1-yl)phenol
InChIKey: YLKVIMNNMLKUGJ-FPLPWBNLSA-N
SMILES: OC1=CC=CC(CCCCCCC/C=C\CCCCCC)=C1
Biological Activity: Cardanol monoene (Cardanol C15:1) is a phenolic compound which can be found in cashew nut shell liquid. Cardanol monoene can inhibit cancer cells proliferation, migration, cause S phase arrest, induce apoptosis, ROS production and mitochondrial depolarization. Cardanol monoene downregulates MMP-2, MMP-9, cyclinA1 expression, regulates CDK2, p53, Bax, cytochrome c, cleaved caspase-3, cleaved PARP, Apaf-1 expression and Bax/Bcl-2 ratio. Cardanol monoene shows weak DPPH radical scavenging activity and AChE inhibition activity. Cardanol monoene is lethal to Artemia salina nauplii. Cardanol monoene. Cardanol monoene can be used for the research of cancer, infection and inflamation[1][2].
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Cardanol monoene | Cardanol monoene (Cardanol C15:1) is a phenolic compound which can be found in cashew nut shell liquid. Cardanol monoene can inhibit cancer cells proliferation, migration, cause S phase arrest, induce apoptosis, ROS production and mitochondrial depolarization. Cardanol monoene downregulates MMP-2, MMP-9, cyclinA1 expression, regulates CDK2, p53, Bax, cytochrome c, cleaved caspase-3, cleaved PARP, Apaf-1 expression and Bax/Bcl-2 ratio. Cardanol monoene shows weak DPPH radical scavenging activity and AChE inhibition activity. Cardanol monoene is lethal to Artemia salina nauplii. Cardanol monoene. Cardanol monoene can be used for the research of cancer, infection and inflamation. | |||||||||||||||||||||
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- [1]. Su WC, et al. Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid. J Agric Food Chem. 2017;65(28):5620-5631. [Content Brief]
- [2]. Rodrigues Valério RB, et al. Unsaturation-Driven Modulation of Antioxidant and Acetylcholinesterase Inhibitory Activities of Cardanol Derivatives. Bioengineering (Basel). 2025;12(12):1316. Published 2025 Dec 1. [Content Brief]
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