501693-25-0

GW768505A free base Chemical Structure
501693-25-0

Chemical Structure

GW768505A free base

  • CAS No.: 501693-25-0
  • Formula:C27H19F4N5O3
  • Molecular Weight:537.47

IUPAC Name: 1-(4-(4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea

InChIKey: FGZIONRFHVNRJB-UHFFFAOYSA-N

SMILES: O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C3=C(C4=CC=C(OC)C=C4)OC5=NC=NC(N)=C53)C=C2

Biological Activity: GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2, with a pIC50 of 7.81 for VEGFR2. GW768505A free base has anti-angiogenic activity[1].

Cat. No. Product Name Purity Description Pricing
HY-125741 		GW768505A free base 99.26% GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2, with a pIC50 of 7.81 for VEGFR2. GW768505A free base has anti-angiogenic activity.
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