51165-07-2
51165-07-2
Chemical Structure
Substance P (6-11)
- CAS No.: 51165-07-2
- Formula:C36H52N8O7S
- Molecular Weight:740.91
InChIKey: JRJICHIAKDIPMB-ZIUUJSQJSA-N
SMILES: CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](N)CCC(N)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O
Biological Activity: Substance P (6-11) is the C-terminal hexapeptideamide of Substance P (HY-P0201). Substance P (6-11) binds to NK-1 tachykinin receptor. Substance P (6-11) shows depolarization of motoneurons and a hypotensive effect[1][2].
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Substance P (6-11) | Substance P (6-11) is the C-terminal hexapeptideamide of Substance P (HY-P0201). Substance P (6-11) binds to NK-1 tachykinin receptor. Substance P (6-11) shows depolarization of motoneurons and a hypotensive effect. | |||||||||||||||||||||
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References
- [1]. Y Torrens, et al. Substance P(6-11) and natural tachykinins interact with septide-sensitive tachykinin receptors coupled to a phospholipase C in the rat urinary bladder. Neuropeptides. 1997 Jun;31(3):243-51. [Content Brief]
- [2]. Y Chiba, et al. Effects of substance P and substance P-(6-11) on hormone release from isolated perfused pancreas: their opposite actions on rat and canine islets. Endocrinology. 1985 Nov;117(5):1996-2000. [Content Brief]
Keywords
