51165-11-8
51165-11-8
Chemical Structure
Substance P (3-11)
- CAS No.: 51165-11-8
- Formula:C52H79N13O11S
- Molecular Weight:1094.33
InChIKey: ILKQEKBZKBJDPT-PVEGFDORSA-N
SMILES: O=C(N1[C@@H](CCC1)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CC=CC=C3)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N
Biological Activity: Substance P (3-11) is a substance P (SP) fragment peptide that can cross the BBB. Substance P (3-11) has contracting activities on guinea pig ileum. Substance P (3-11) also promotes human monocyte chemotaxis [1][2][5].
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Substance P (3-11) | Substance P (3-11) is a substance P (SP) fragment peptide that can cross the BBB. Substance P (3-11) has contracting activities on guinea pig ileum. Substance P (3-11) also promotes human monocyte chemotaxis . | |||||||||||||||||||||
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References
- [1]. Yanaihara N, et al. Immunological aspects of secretin, substance P, and VIP. Gastroenterology. 1977 Apr;72(4 Pt.2):803-10. [Content Brief]
- [2]. Chappa AK, et al. Characteristics of substance P transport across the blood-brain barrier. Pharm Res. 2006 Jun;23(6):1201-8. [Content Brief]
- [5]. Freed AL, et al. Investigation of substance P transport across the blood-brain barrier. Peptides. 2002 Jan;23(1):157-65. [Content Brief]
