514-36-3
Chemical Structure
Fludrocortisone acetate
Synonym(s): 9α-Fludrocortisone acetate; 9α-Fluorcortisol acetate
- No. CAS: 514-36-3
- Formula:C23H31FO6
- Molecular Weight:422.49
IUPAC Name: 2-((8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
InChIKey: SYWHXTATXSMDSB-GSLJADNHSA-N
SMILES: C[C@@]12[C@](C(COC(C)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3(F)[C@@H](O)C2)=O
Biological Activity: Fludrocortisone acetate (9α-Fludrocortisone acetate) is an orally active synthetic mineralocorticoid. Fludrocortisone acetate can effectively control sodium retention. Fludrocortisone acetate is used in studies of cardiac injury, adrenal insufficiency and orthostatic hypotension[1][2][3].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Fludrocortisone acetate | 99.59% | Fludrocortisone acetate (9α-Fludrocortisone acetate) is an orally active synthetic mineralocorticoid. Fludrocortisone acetate can effectively control sodium retention. Fludrocortisone acetate is used in studies of cardiac injury, adrenal insufficiency and orthostatic hypotension. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Fludrocortisone acetate (Standard) | 98.48% | Fludrocortisone acetate (Standard) is the analytical standard of Fludrocortisone acetate. This product is intended for research and analytical applications. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Fludrocortisone acetate-d5 | 97.89% | Fludrocortisone acetate-d5 is deuterium labeled Fludrocortisone acetate. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Fitzgerald M, et al. Mineralocorticoids restore quiescent morphology and reduce VEGF receptor expression in inflamed choroidal endothelial cells in vitro. Ophthalmic Res. 2009;41(1):44-52. [Content Brief]
- [2]. Sarker M, et al. Astaxanthin protects fludrocortisone acetate-induced cardiac injury by attenuating oxidative stress, fibrosis, and inflammation through TGF-β/Smad signaling pathway. Biomed Pharmacother. 2024 Dec;181:117703. [Content Brief]
- [3]. Djajadiningrat-Laanen SC, et al. Urinary aldosterone to creatinine ratio in cats before and after suppression with salt or fludrocortisone acetate. J Vet Intern Med. 2008 Nov-Dec;22(6):1283-8. [Content Brief]
