524-15-2
Chemical Structure
γ-Fagarine
- CAS No.: 524-15-2
- Formula:C13H11NO3
- Molecular Weight:229.23
IUPAC Name: 4,8-dimethoxyfuro[2,3-b]quinoline
InChIKey: KFBCTNNQFGONHB-UHFFFAOYSA-N
SMILES: COC1=C2N=C(OC=C3)C3=C(OC)C2=CC=C1
Biological Activity: γ-Fagarine is a furoquinoline alkaloid naturally occurring in Rutae Herba. γ-Fagarine has strong anti-HCV activities with IC50 of 20.4 μg/mL and is also a sister chromatid exchanges (SCEs) inducer[1][2].
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γ-Fagarine | 99.73% | γ-Fagarine is a furoquinoline alkaloid naturally occurring in Rutae Herba. γ-Fagarine has strong anti-HCV activities with IC50 of 20.4 μg/mL and is also a sister chromatid exchanges (SCEs) inducer. | ||||||||||||||||||||
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- [1]. Tutik Sri Wahyuni, et al. Inhibition of Hepatitis C Virus Replication by Chalepin and Pseudane IX Isolated From Ruta Angustifolia Leaves. Fitoterapia. 2014 Dec;99:276-83. [Content Brief]
- [2]. O Schimmer, et al. The SCE-inducing Potency of the Furoquinoline Alkaloid, Gamma-Fagarine, and a Gamma-Fagarine-Containing Tincture From Rutae Herba, in Cultured Human Lymphocytes. Mutagenesis. 1989 Nov;4(6):467-70. [Content Brief]
Keywords