53-83-8
53-83-8
Chemical Structure
6-Thioinosine Phosphate
Synonym(s): Thioinosinic acid
- No. CAS: 53-83-8
- Formula:C10H13N4O7PS
- Molecular Weight:364.27
IUPAC Name: ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-thioxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate
InChIKey: ZKRFOXLVOKTUTA-KQYNXXCUSA-N
SMILES: O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N2C=NC3=C2N=CNC3=S
Biological Activity: 6-Thioinosine Phosphate (Thioinosinic acid) is an intermediate metabolite of azathioprine (HY-B0256). Azathioprine is a purine analog immunosuppressive drug[1].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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6-Thioinosine Phosphate | 90.00% | 6-Thioinosine Phosphate (Thioinosinic acid) is an intermediate metabolite of azathioprine (HY-B0256). Azathioprine is a purine analog immunosuppressive drug. | ||||||||||||||||||||
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Inosinic acid (Standard) | 99.31% | Inosinic acid (Standard) is the analytical standard of Inosinic acid. This product is intended for research and analytical applications. Inosinic acid is an endogenous metabolite. Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs. | ||||||||||||||||||||
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6-Thioinosine | 99.31% | 6-Thioinosine (6TI) is a purine antimetabolite and an anti-adipogenic agent. 6-Thioinosine reduces the mRNA levels of PPARγ and C/EBPα and downregulates the mRNA levels of PPARγ target genes (LPL, CD36, aP2, and LXRα). 6-Thioinosine exerts its anti-adipogenic effects by downregulating PPARγ through JNK-dependent iNOS upregulation. 6-Thioinosine can be used to study adipocyte dysfunction. | ||||||||||||||||||||
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6-Cl-5'-PuMP | 6-Cl-5'-PuMP is a reactive analogue of adenosine 5’-O-monophosphate (5’-AMP), and is suitable for modifying position 6 using various nucleophiles. | |||||||||||||||||||||
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6-T-5'-GMP | 6-T-5'-GMP (6-Thioguanosine monophosphate) is an analogue of guanosine-5'-O-monophosphate (5'-GMP) and a metabolite of an immunosuppressive drug, Azathioprine (HY-B0256). | |||||||||||||||||||||
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Adenosine 5'-monophosphate monohydrate | 99.81% | Adenosine 5'-monophosphate monohydrate is an adenosine A1 receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against HSV-1 and HSV-2. | ||||||||||||||||||||
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Adenosine monophosphate (Standard) | 99.69% | Adenosine monophosphate (Standard) is the analytical standard of Adenosine monophosphate (HY-A0181). This product is intended for research and analytical applications. Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction. | ||||||||||||||||||||
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Fludarabine phosphate (Standard) | ≥98% | Fludarabine (phosphate) (Standard) is the analytical standard of Fludarabine (phosphate). This product is intended for research and analytical applications. Fludarabine (phosphate) is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis. | ||||||||||||||||||||
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Vidarabine phosphate | 99.44% | Vidarabine phosphate (ara-AMP; ara-A 5'-monophosphate) is a purine nucleoside antiviral agent and a prodrug of Vidarabine (HY-B0277). Vidarabine phosphate is rapidly converted into the antiviral active Vidarabine in vivo, which selectively inhibits viral DNA polymerase and cellular ribonucleotide reductase, thereby blocking viral replication. Vidarabine phosphate also exhibits antifungal activity, induces late-stage cellular apoptosis, and causes cell cycle arrest. Vidarabine phosphate can be used in research related to severe chronic active Epstein-Barr virus (EBV) infection, herpes infection, and candidiasis. | ||||||||||||||||||||
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5'-Guanylic acid | 99.96% | 5'-Guanylic acid is a purine nucleotide that participates in physiological processes such as energy metabolism, signal transduction, and gene expression regulation. 5'-Guanylic acid regulates the expression of genes related to fatty acid metabolism. 5'-Guanylic acid is the weak agonist for ionotropic glutamate receptors (iGluR), reduces the activity of the glutamatergic system and exhibits neuroprotective effect. 5'-Guanylic acid also causes neuronal cell death at high concentrations. | ||||||||||||||||||||
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ara-GMP | ara-GMP (ara-G monophosphate) is a metabolite of Arabinosylguanine (ara-G) (HY-N0097A). ara-GMP incorporates into replicating DNA , initiates S phase-specific apoptosis. ara-GMP can be used for the research of cancer, such as T-cell acute lymphoblastic leukemia. | |||||||||||||||||||||
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