53501-41-0
53501-41-0
Chemical Structure
PIT-1
- CAS No.: 53501-41-0
- Formula:C14H10ClN3O4S
- Molecular Weight:351.76
IUPAC Name: N-((3-chloro-2-hydroxy-5-nitrophenyl)carbamothioyl)benzamide
InChIKey: RIGXBXPAOGDDIG-UHFFFAOYSA-N
SMILES: O=C(NC(NC1=CC([N+]([O-])=O)=CC(Cl)=C1O)=S)C2=CC=CC=C2
Biological Activity: PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PIT-1 | 98.08% | PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo. | ||||||||||||||||||||
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PIT-1 (Standard) | ≥98% | PIT-1 (Standard) is the analytical standard of PIT-1. This product is intended for research and analytical applications. PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.75
HY-124348DM-PIT-1 -
Similarity Score 0.65
HY-W274807TM-2-51 -
Similarity Score 0.64
HY-150588InhA-IN-3 -
Similarity Score 0.64
HY-162934TFCP2L1-IN-1 -
Similarity Score 0.62
HY-16578RGW9662 (Standard) -
Similarity Score 0.62
HY-B0497BNiclosamide monohydrate -
Similarity Score 0.62
HY-B0497BSNiclosamide-13C6 monohydrate -
Similarity Score 0.62
HY-16711SB225002 -
Similarity Score 0.62
HY-B0497GNiclosamide (GMP) -
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