53501-41-0
53501-41-0
Chemical Structure
PIT-1
- CAS No.: 53501-41-0
- Formula:C14H10ClN3O4S
- Molecular Weight:351.76
IUPAC Name: N-((3-chloro-2-hydroxy-5-nitrophenyl)carbamothioyl)benzamide
InChIKey: RIGXBXPAOGDDIG-UHFFFAOYSA-N
SMILES: O=C(NC(NC1=CC([N+]([O-])=O)=CC(Cl)=C1O)=S)C2=CC=CC=C2
Biological Activity: PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo[1].
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PIT-1 | 98.08% | PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo. | ||||||||||||||||||||
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PIT-1 (Standard) | ≥98% | PIT-1 (Standard) is the analytical standard of PIT-1. This product is intended for research and analytical applications. PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo. | ||||||||||||||||||||
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References
Keywords
