2. Anti-infection
  3. Bacterial
  4. InhA-IN-3

InhA-IN-3 (Compound TU12) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 17.7 μM.

For research use only. We do not sell to patients.

InhA-IN-3

InhA-IN-3 Chemical Structure

CAS No. : 900701-83-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
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Based on 1 publication(s) in Google Scholar

InhA-IN-3 Related Antibodies

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Description

InhA-IN-3 (Compound TU12) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 17.7 μM[1].

IC50 & Target

IC50: 17.7 μM (InhA)[1]
In Vitro

InhA-IN-3 (Compound TU12) shows antitubercular activity with a MIC of 0.78±0.59 µg/mL against Mycobacterium tuberculosis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

InhA-IN-3 Related Antibodies
Molecular Weight

321.78

Formula

C14H12ClN3O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

S=C(NC1=CC=C([N+]([O-])=O)C=C1)NCC2=CC=CC=C2Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (388.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1077 mL 15.5386 mL 31.0771 mL
5 mM 0.6215 mL 3.1077 mL 6.2154 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1077 mL 15.5386 mL 31.0771 mL 77.6928 mL
5 mM 0.6215 mL 3.1077 mL 6.2154 mL 15.5386 mL
10 mM 0.3108 mL 1.5539 mL 3.1077 mL 7.7693 mL
15 mM 0.2072 mL 1.0359 mL 2.0718 mL 5.1795 mL
20 mM 0.1554 mL 0.7769 mL 1.5539 mL 3.8846 mL
25 mM 0.1243 mL 0.6215 mL 1.2431 mL 3.1077 mL
30 mM 0.1036 mL 0.5180 mL 1.0359 mL 2.5898 mL
40 mM 0.0777 mL 0.3885 mL 0.7769 mL 1.9423 mL
50 mM 0.0622 mL 0.3108 mL 0.6215 mL 1.5539 mL
60 mM 0.0518 mL 0.2590 mL 0.5180 mL 1.2949 mL
80 mM 0.0388 mL 0.1942 mL 0.3885 mL 0.9712 mL
100 mM 0.0311 mL 0.1554 mL 0.3108 mL 0.7769 mL
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InhA-IN-3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

InhA-IN-3900701-83-9BacterialMycobacterium tuberculosisInhAenoyl ACP-reductaseInhibitorinhibitorinhibit

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