53749-60-3
Chemical Structure
Substance P (4-11)
- CAS. Nr.: 53749-60-3
- Formula:C46H67N11O10S
- Molecular Weight:966.16
InChIKey: XVTHVTVZLLFSPI-QJCLFNHPSA-N
SMILES: CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@@H]2CCCN2)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O
Biological Activity: Substance P (4-11), the C-terminus fragment of Substance P (HY-P0201), is a Substance P agonist that shows highly selective for NK1 receptors[1][2].
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Substance P (4-11) | Substance P (4-11), the C-terminus fragment of Substance P (HY-P0201), is a Substance P agonist that shows highly selective for NK1 receptors. | |||||||||||||||||||||
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- [1]. D G Payan, et al. Specific stimulation of human T lymphocytes by substance P. J Immunol. 1983 Oct;131(4):1613-5. [Content Brief]
- [2]. L Wang, et al. Substance P induces ion secretion in mouse small intestine through effects on enteric nerves and mast cells. Am J Physiol. 1995 Jul;269(1 Pt 1):G85-92. [Content Brief]
Keywords