541-91-3
541-91-3
Chemical Structure
Muscone
- CAS. Nr.: 541-91-3
- Formula:C16H30O
- Molecular Weight:238.41
IUPAC Name: 3-methylcyclopentadecan-1-one
InChIKey: ALHUZKCOMYUFRB-UHFFFAOYSA-N
SMILES: O=C1CC(C)CCCCCCCCCCCC1
Biological Activity: Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Muscone | 98.0% | Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate. | ||||||||||||||||||||
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Muscone (Standard) | ≥98% | Muscone (Standard) is the analytical standard of Muscone. This product is intended for research and analytical applications. Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate. | ||||||||||||||||||||
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M50054 (Standard) | ≥98% | M50054 (Standard) is the analytical standard of M50054. This product is intended for research and analytical applications. M50054 is a potent inhibitor of apoptosis. M50054 inhibits Etoposide-induced caspase-3 activation of U937 cells with an IC50 of 79 μg/mL. M50054 does not directly inhibit the enzymatic activity of caspase-3. M50054 can be used for the research anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia. | ||||||||||||||||||||
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NC1153 | NC1153 is a Mannich base with the activity to block IL-2-induced JAK3 activation and its downstream substrate STAT5a/b. NC1153 effectively prolongs the survival of kidney transplants in MHC/non-MHC mismatched rats. NC1153 promotes long-term graft survival and includes multiple toxicity protection for recipients. NC1153 combined with cyclosporine A (CsA) can synergistically prolong graft survival without producing nephrotoxicity, myelotoxicity or lipotoxicity. | |||||||||||||||||||||
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2-(5,8-Tetradecadienyl)cyclobutanone | 2-(5,8-Tetradecadienyl)cyclobutanone (HMDB 37519) is a non-functional small molecule that can be extracted from herbal decoctions. | |||||||||||||||||||||
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Nectaryl | Nectaryl is a flavor with the fruity aroma of peaches and apricots. Nectaryl is a mixture of 4 stereoisomers, among which the (R)-configured isomer at the C (2) position contributes the most to the overall odor. Nectaryl can be used as a flavor ingredient in cosmetic formulations and laundry detergents. | |||||||||||||||||||||
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Curdione (Standard) | ≥98% | Curdione (Standard) is the analytical standard of Curdione. This product is intended for research and analytical applications. Curdione ((+)-Curdione) is an orally active sesquiterpenoid. Curdione inhibits platelet aggregation. Curdione induces ferroptosis in colorectal cancer via m6A methylation mediated by METTL14 and YTHDF2. Curdione inhibits ferroptosis in Isoproterenol (HY-B0468)-induced myocardial infarction by regulating the Keap1/Trx1/GPX4 signaling pathway, suppressing oxidative stress (ROS) and apoptosis. Curdione ameliorates Doxorubicin (HY-15142)-induced cardiotoxicity by inhibiting oxidative stress (ROS) and activating the Nrf2/HO-1 pathway. Curdione ameliorates sepsis-induced lung injury by inhibiting platelet-mediated neutrophil extracellular trap formation. Curdione ameliorates Bleomycin (HY-17565A)-induced pulmonary fibrosis by inhibiting TGF-β-induced fibroblast-to-myofibroblast differentiation. Curdione exhibits neuroprotective effects against focal cerebral ischemia-reperfusion injury in rats. Curdione exerts antiproliferative effects against human uterine leiomyosarcoma by targeting IDO1. Curdione protects vascular endothelial cells and atherosclerosis by regulating DNMT1-mediated ERBB4 promoter methylation. Curdione inhibits inducible prostaglandin E2 production (IC50 = 1.1 μM) and cyclooxygenase 2 expression. | ||||||||||||||||||||
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Preisocalamendiol | Preisocalamendiol is a plausible precursor of isocalamendiol. Preisocalamendiol can be isolated from Acorus calamus L. | |||||||||||||||||||||
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Neocurdione | Neocurdione is a hepatoprotective sesquiterpene isolated from Curcuma zedoaria rhizome. Neocurdione exerts potent effect on D-galactosamine- (D-Gain) and lipopolysaccharide- (LPS) induced acute liver injury in mice. | |||||||||||||||||||||
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Decylcyclohexane | Decylcyclohexane (N-Decylcyclohexane) is a chemical composition that can be isolated from Spermadictyon suaveolens leaves. | |||||||||||||||||||||
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Dihydroartemisinin diketo aldehyde | Dihydroartemisinin diketo aldehyde is an Artemether (HY-N0402) impurity. | |||||||||||||||||||||
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(R)-(-)-Muscone | 99.01% | (R)-(-)-Muscone, a musk-smelling compound, is an odorant receptor OR5AN1 agonist. | ||||||||||||||||||||
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