545380-34-5
545380-34-5
Chemical Structure
QNZ
Synonym(s): EVP4593
- CAS. Nr.: 545380-34-5
- Formula:C22H20N4O
- Molecular Weight:356.42
IUPAC Name: N4-(4-phenoxyphenethyl)quinazoline-4,6-diamine
InChIKey: IBAKVEUZKHOWNG-UHFFFAOYSA-N
SMILES: NC1=CC2=C(NCCC3=CC=C(OC4=CC=CC=C4)C=C3)N=CN=C2C=C1
Biological Activity: QNZ (EVP4593) shows strong inhibitory effects on NF-κB transcriptional activation and TNF-α production with IC50s of 11 and 7 nM, respectively. QNZ (EVP4593) is a neuroprotective inhibitor of SOC channel.
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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QNZ | 99.28% | QNZ (EVP4593) shows strong inhibitory effects on NF-κB transcriptional activation and TNF-α production with IC50s of 11 and 7 nM, respectively. QNZ (EVP4593) is a neuroprotective inhibitor of SOC channel. | ||||||||||||||||||||
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QNZ (Standard) | ≥98% | QNZ (Standard) is the analytical standard of QNZ. This product is intended for research and analytical applications. QNZ (EVP4593) shows strong inhibitory effects on NF-κB transcriptional activation and TNF-α production with IC50s of 11 and 7 nM, respectively. QNZ (EVP4593) is a neuroprotective inhibitor of SOC channel. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.66
HY-117988SNX2-1-108 -
Similarity Score 0.66
HY-15681ASenexin A hydrochloride -
Similarity Score 0.65
HY-15681Senexin A -
Similarity Score 0.62
HY-178740GI261520A -
Similarity Score 0.60
HY-101053Src Inhibitor 1 -
Similarity Score 0.60
HY-155107ND-011992 -
Similarity Score 0.56
HY-100627APS-2-79 -
Similarity Score 0.55
HY-100627AAPS-2-79 hydrochloride -
Similarity Score 0.55
HY-12990Spautin-1 -
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