546-43-0
546-43-0
Chemical Structure
Alantolactone
Synonym(s): (+)-Alantolactone; Alant camphor; Inula camphor
- CAS No.: 546-43-0
- Formula:C15H20O2
- Molecular Weight:232.32
IUPAC Name: (3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylene-3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(3H)-one
InChIKey: PXOYOCNNSUAQNS-AGNJHWRGSA-N
SMILES: O=C(O[C@@]1([H])[C@]2([H])C=C3[C@@H](C)CCC[C@]3(C)C1)C2=C
Biological Activity: Alantolactone is a selective STAT3 inhibitor, with potent anticancer activity. Alantolactone induces apoptosis in cancer[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Alantolactone | 99.94% | Alantolactone is a selective STAT3 inhibitor, with potent anticancer activity. Alantolactone induces apoptosis in cancer. | ||||||||||||||||||||
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Alantolactone (Standard) | ≥98% | Alantolactone (Standard) is the analytical standard of Alantolactone. This product is intended for research and analytical applications. Alantolactone is a selective STAT3 inhibitor, with potent anticancer activity. Alantolactone induces apoptosis in cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.82
HY-1246701beta-Hydroxyalantolactone -
Similarity Score 0.81
HY-142958NF-κB-IN-2 -
Similarity Score 0.70
HY-123091Ivangustin -
Similarity Score 0.70
HY-N0780RIsoalantolactone (Standard) -
Similarity Score 0.70
HY-N12827(+)-Frullanolide -
Similarity Score 0.69
HY-N1344410β-Hydroxycadina-4,11(13)-dien-12,8β-olide -
Similarity Score 0.68
HY-127003Neoambrosin -
Similarity Score 0.68
HY-N17252-Desoxy-4-epi-pulchellin -
Similarity Score 0.68
HY-N1326Santamarine -
Explore the MedChemAI to find more analogs
References
- [1]. Khan M, et al. Alantolactone induces apoptosis in HepG2 cells through GSH depletion, inhibition of STAT3 activation, and mitochondrial dysfunction. Biomed Res Int. 2013;2013:719858. [Content Brief]
- [2]. Chun J, et al. Alantolactone selectively suppresses STAT3 activation and exhibits potent anticancer activity in MDA-MB-231 cells. Cancer Lett. 2015 Feb 1;357(1):393-403. [Content Brief]
