54810-23-0
54810-23-0
Chemical Structure
Loxapine hydrochloride
- CAS No.: 54810-23-0
- Formula:C18H19Cl2N3O
- Molecular Weight:364.27
IUPAC Name: 2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine hydrochloride
InChIKey: JSXBVMKACNEMKY-UHFFFAOYSA-N
SMILES: CN1CCN(C2=NC3=CC=CC=C3OC4=CC=C(Cl)C=C24)CC1.[H]Cl
Biological Activity: Loxapine hydrochloride is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent[1][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Loxapine hydrochloride | Loxapine hydrochloride is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Loxapine-d8 | 99.13% | Loxapine-d8 is the deuterium labeled Loxapine. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Loxapine-d8 hydrochloride | Loxapine-d8 hydrochloride is the deuterium labeled Loxapine. Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Singh AN, et al. A neurochemical basis for the antipsychotic activity of loxapine: interactions with dopamine D1, D2, D4 and serotonin 5-HT2 receptor subtypes. J Psychiatry Neurosci. 1996 Jan;21(1):29-35. [Content Brief]
- [4]. Keating GM. Loxapine inhalation powder: a review of its use in the acute treatment of agitation in patients with bipolar disorder or schizophrenia. CNS Drugs. 2013 Jun;27(6):479-89. [Content Brief]
