550-82-3
Chemical Structure
Resazurin
Synonym(s): Diazoresorcinol
- CAS No.: 550-82-3
- Formula:C12H7NO4
- Molecular Weight:229.19
IUPAC Name: 7-hydroxy-3-oxo-3H-phenoxazine 10-oxide
InChIKey: PLXBWHJQWKZRKG-UHFFFAOYSA-N
SMILES: O=C1C=CC2=[N+](C3=C(OC2=C1)C=C(C=C3)O)[O-]
Biological Activity: Resazurin (Diazoresorcinol) is a water-soluble, non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal)[1][2].
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Resazurin | Resazurin (Diazoresorcinol) is a water-soluble, non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal). | |||||||||||||||||||||
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- [1]. Silva FSG, et al. Determination of Metabolic Viability and Cell Mass Using a Tandem Resazurin/Sulforhodamine B Assay. Curr Protoc Toxicol. 2016 May 4;68:2.24.1-2.24.15. [Content Brief]
- [2]. Rampersad SN. Multiple applications of Alamar Blue as an indicator of metabolic function and cellular health in cell viability bioassays. Sensors (Basel). 2012;12(9):12347-60. [Content Brief]
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