550-83-4
Chemical Structure
Propoxycaine hydrochloride
- CAS 番号: 550-83-4
- Formula:C16H27ClN2O3
- Molecular Weight:330.85
IUPAC Name: 2-(diethylamino)ethyl 4-amino-2-propoxybenzoate hydrochloride
InChIKey: GITPCGSPKUQZTE-UHFFFAOYSA-N
SMILES: O=C(OCCN(CC)CC)C1=CC=C(N)C=C1OCCC.[H]Cl
Biological Activity: Propoxycaine hydrochloride is a voltage-gated sodium channel inhibitor. Propoxycaine hydrochloride delays monophasic A spike action potential recovery. Propoxycaine hydrochloride increases bulk lateral, rotational, and annular lipid fluidity in neuronal membrane lipid bilayers, with greater inner monolayer fluidization, and induces membrane protein clustering. Propoxycaine hydrochloride can be used for the research of pain[1][2][3].
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Propoxycaine hydrochloride | 99.70% | Propoxycaine hydrochloride is a voltage-gated sodium channel inhibitor. Propoxycaine hydrochloride delays monophasic A spike action potential recovery. Propoxycaine hydrochloride increases bulk lateral, rotational, and annular lipid fluidity in neuronal membrane lipid bilayers, with greater inner monolayer fluidization, and induces membrane protein clustering. Propoxycaine hydrochloride can be used for the research of pain. | ||||||||||||||||||||
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Similarity Score 0.82
HY-66012RProparacaine hydrochloride (Standard) -
Similarity Score 0.80
HY-66012AProparacaine -
Similarity Score 0.79
HY-105613Metabutoxycaine -
Similarity Score 0.78
HY-B1288ROxybuprocaine hydrochloride (Standard) -
Similarity Score 0.78
HY-164631EL20 -
Similarity Score 0.78
HY-B1288AOxybuprocaine -
Similarity Score 0.75
HY-B1604Chloroprocaine hydrochloride -
Similarity Score 0.75
HY-103143SDZ 205-557 hydrochloride -
Similarity Score 0.74
HY-112042Aspirin Trelamine -
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References
- [1]. TRUANT AP, et al. Differential physical-chemical and neuropharmacologic properties of local anesthetic agents. Anesth Analg. 1959 Nov-Dec;38:478-84. [Content Brief]
- [2]. TAINTER ML, et al. New local anesthetic solutions containing propoxycaine. J Am Dent Assoc. 1955 Jul;51(1):19-27. [Content Brief]
- [3]. Lee JH, et al. The effect of propoxycaine.HCl on the physical properties of neuronal membranes. Chem Phys Lipids. 2008;154(1):19-25. [Content Brief]
