1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. Propoxycaine hydrochloride

Propoxycaine hydrochloride 

Cat. No.: HY-B1243 Purity: 99.98%
Handling Instructions

Propoxycaine hydrochloride inhibits voltage-gated sodium channels, and thereby inhibits the ionic flux required for the initiation and conduction of impulses. Propoxycaine hydrochloride application can lead to a loss of sensation.

For research use only. We do not sell to patients.

Propoxycaine hydrochloride Chemical Structure

Propoxycaine hydrochloride Chemical Structure

CAS No. : 550-83-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 209 In-stock
Estimated Time of Arrival: December 31
50 mg USD 190 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Propoxycaine hydrochloride inhibits voltage-gated sodium channels, and thereby inhibits the ionic flux required for the initiation and conduction of impulses. Propoxycaine hydrochloride application can lead to a loss of sensation.

IC50 & Target

IC50: sodium channel

Molecular Weight

330.85

Formula

C₁₆H₂₇ClN₂O₃

CAS No.

550-83-4

SMILES

O=C(OCCN(CC)CC)C1=CC=C(N)C=C1OCCC.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (151.13 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0225 mL 15.1126 mL 30.2252 mL
5 mM 0.6045 mL 3.0225 mL 6.0450 mL
10 mM 0.3023 mL 1.5113 mL 3.0225 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.56 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.56 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.56 mM); Clear solution

*All of the co-solvents are provided by MCE.

Purity: 99.98%

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PropoxycaineSodium ChannelNa channelsNa+ channelssodiumchannelsensationInhibitorinhibitorinhibit

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Product Name:
Propoxycaine hydrochloride
Cat. No.:
HY-B1243
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