56-04-2
Chemical Structure
Methylthiouracil
Synonym(s): MTU
- CAS. Nr.: 56-04-2
- Formula:C5H6N2OS
- Molecular Weight:142.18
IUPAC Name: 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
InChIKey: HWGBHCRJGXAGEU-UHFFFAOYSA-N
SMILES: O=C(C=C(C)N1)NC1=S
Biological Activity: Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Methylthiouracil | 98.0% | Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2. | ||||||||||||||||||||
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Methylthiouracil (Standard) | 99.58% | Methylthiouracil (Standard) is the analytical standard of Methylthiouracil. This product is intended for research and analytical applications. Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2. | ||||||||||||||||||||
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Iodothiouracil | Iodothiouracil exhibits high selectivity for melanoma, remains stable in the melanin in melanoma cells, and localizes remote secondary metastases of melanoma. Iodothiouracil can be used for melanoma imaging when labeled with iodine-123, and can be used for radiation therapy when labeled with iodine-131. | |||||||||||||||||||||
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4-Amino-6-hydroxy-2-mercaptopyrimidine mono hydrate | 99.72% | 4-Amino-6-hydroxy-2-mercaptopyrimidine mono hydrate is a drug intermediate for synthesis of various active compounds. | ||||||||||||||||||||
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Propylthiouracil (Standard) | 99.60% | Propylthiouracil (Standard) is the analytical standard of Propylthiouracil. This product is intended for research and analytical applications. Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research. | ||||||||||||||||||||
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2-Thiouracil-13C,15N2 | 2-Thiouracil-13C,15N2 is the 13C, 15N labeled 2-Thiouracil. 2-Thiouracil (Thiouracil) is an antithyroid compound. 2-Thiouracil can function as a highly specific melanoma seeker. 2-Thiouracil is a selective inhibitor of neuronal nitric oxide synthase (nNOS) with a Ki of 20 μM. | |||||||||||||||||||||
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Uracil-d1-1 | Uracil-d1-1 is the deuterium labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. | |||||||||||||||||||||
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Thymine-15N2 | Thymine-15N2 is the 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | |||||||||||||||||||||
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4,6-Dimethylpyrimidin-2(1H)-one (Standard) | ≥98% | 4,6-Dimethylpyrimidin-2(1H)-one (Standard) is the analytical standard of 4,6-Dimethylpyrimidin-2(1H)-one. This product is intended for research and analytical applications. | ||||||||||||||||||||
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6-Amino-4-hydroxy-2-mercaptopyrimidine-13C | 6-Amino-4-hydroxy-2-mercaptopyrimidine-13C (6-Amino-2-thiouracil Monohydrate-13C) is the 13C-labeled 6-Amino-4-hydroxy-2-mercaptopyrimidine (HY-75601). | |||||||||||||||||||||
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6-Methyluracil (Standard) | ≥98% | 6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo. | ||||||||||||||||||||
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