57775-22-1
57775-22-1
Chemical Structure
Etoperidone hydrochloride
- CAS No.: 57775-22-1
- Formula:C19H29Cl2N5O
- Molecular Weight:414.37
IUPAC Name: 2-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-4,5-diethyl-2,4-dihydro-3H-1,2,4-triazol-3-one hydrochloride
InChIKey: BHKPQZVLIZKSAG-UHFFFAOYSA-N
SMILES: O=C1N(CCCN2CCN(CC2)C3=CC(Cl)=CC=C3)N=C(CC)N1CC.Cl
Biological Activity: Etoperidone hydrochloride, an antidepressant agent, is an orally active serotonin and nor-adrenaline re-uptake antagonist. Etoperidone hydrochloride shows Kd values of 36 nM, 38 nM, 85 nM, and 570 nM for 5-HT2 receptor, α1-adrenergic receptor, 5-HT1A receptor, and α2-adrenergic receptor, respectively[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Etoperidone hydrochloride | Etoperidone hydrochloride, an antidepressant agent, is an orally active serotonin and nor-adrenaline re-uptake antagonist. Etoperidone hydrochloride shows Kd values of 36 nM, 38 nM, 85 nM, and 570 nM for 5-HT2 receptor, α1-adrenergic receptor, 5-HT1A receptor, and α2-adrenergic receptor, respectively. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Etoperidone-d8 hydrochloride | Etoperidone-d8 (hydrochloride) is the deuterium labeled Etoperidone hydrochloride. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. B Cusack, et al. Binding of antidepressants to human brain receptors: focus on newer generation compounds. Psychopharmacology (Berl). 1994 May;114(4):559-65. [Content Brief]
- [2]. G W Caldwell, et al. Evaluation of the absorption, excretion and metabolism of [14C] etoperidone in man. Xenobiotica. 2001 Nov;31(11):823-39. [Content Brief]
