5875-35-4
5875-35-4
Chemical Structure
γ-Glutamylserine
Synonym(s): γ-Glu-Ser
- CAS No.: 5875-35-4
- Formula:C8H14N2O6
- Molecular Weight:234.21
IUPAC Name: N5-((S)-1-carboxy-2-hydroxyethyl)-L-glutamine
InChIKey: SQBNIUOYNOKDTI-WHFBIAKZSA-N
SMILES: OC([C@H](CO)NC(CC[C@H](N)C(O)=O)=O)=O
Biological Activity: γ-Glutamylserine (γ-Glu-Ser) is a calcium receptor activator. γ-Glutamylserine can be used for Parkinson's disease research, as well as diabetes or obesity study[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
γ-Glutamylserine | 99.95% | γ-Glutamylserine (γ-Glu-Ser) is a calcium receptor activator. γ-Glutamylserine can be used for Parkinson's disease research, as well as diabetes or obesity study. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Gamma-glutamylcysteine | 98.53% | Gamma-glutamylcysteine (γ-Glu-Cys) is an orally active, blood-brain barrier permeable dipeptide. Gamma-glutamylcysteine activates AMPK, SIRT1, IL-4/STAT6, AC/cAMP/PI3K, IGF-1R/IRS1/PI3K, and Nrf2 signaling pathways; it inhibits NF-κB, JAK1/STAT1/3, MAPKs, cadmium-induced p38 MAPK, JNK, and PI3K/Akt signaling pathways. Gamma-glutamylcysteine regulates macrophage polarization, modulates the trafficking of CD36 and GLUT4, induces glutathione synthesis, improves metabolic dysfunction, reduces lipid deposition, ameliorates glucose homeostasis, inhibits apoptosis (Apoptosis), stabilizes mitochondria, suppresses lipid peroxidation, iron accumulation and ferroptosis (Ferroptosis), reduces ds-HMGB1 levels, reverses mechanical hyperalgesia, and alleviates hepatic lipid droplet formation. Gamma-glutamylcysteine is applicable to research related to inflammatory bowel disease, type 2 diabetes, cadmium-induced neurotoxicity, Alzheimer's disease, cerebral ischemia/reperfusion injury, neuropathy, and alcoholic liver disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Methylseleno carboxyethylglutamine | Methylselenocarboxyethylglutamine (GMSeC) is an organic selenium compound that shows no in vitro anti-cancer activity against colon cancer. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
L-γ-Glutamyl-L-glutamic acid | 99.90% | L-γ-Glutamyl-L-glutamic acid (D-γ-Glu-Glu) is a γ-glutamyl dipeptide. L-γ-Glutamyl-L-glutamic acid exists in the acid hydrolysate of poly-γ-glutamic acid produced by Bacillus subtilis F-2-01. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
D-γ-Glutamyl-D-glutamic acid | 98.85% | D-γ-Glutamyl-D-glutamic acid is a poly(γ-glutamic acid) of clusters of D- and D-glutamic acid repeating units in a linear chain. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Gamma-glutamyl-beta-cyanoalanine | Gamma-glutamyl-beta-cyanoalanine (γ-Glutamyl-β-cyanoalanine), a dipeptide, is a neurotoxin found in Seeds of common vetch. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
γ-Glutamylornithine (Standard) | ≥98% | γ-Glutamylornithine is the urine excreta of patients with HHH syndrome (hyperuricemia, hyperaminemia, and hypercitrullinuria) and rotary atrophy associated with hyperuricemia. Increased levels of endogenous ornithine increase levels of γ-Glutamylornithine in the urine. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
gamma-Glutamylaspartic acid | 98.88% | gamma-Glutamylaspartic acid (γ-Glu-Asp) is a γ-glutamyl dipeptide with kokumi activities. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Gamma-Glu-Abu | Gamma-Glu-Abu is a CaSR activator with an EC50 of 0.21 μM (in HEK-293 cells). Gamma-Glu-Abu interacts with the extracellular venus flytrap domain of hCaSR via its N-terminal γ-L-glutamyl residue, the neutral aliphatic side chain of the Abu residue, and the C-terminal carboxylic acid group. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
H-γ-Glu-Leu-OH | 99.21% | H-γ-Glu-Leu-OH (γ-Glu-Leu) is a dipeptide consisting of γ-glutamic acid and leucine, terminated by a hydroxyl group. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Glu-Ser | 97.33% | Glu-Ser is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Nagasaki Hiroaki, et al. Low-fat foods containing amino acids and peptides: World Intellectual Property Organization, WO2008139945. 2008-11-20.
- [2]. Chen Xianyang, et al. Application of taurine and ceramide biomarker in detection reagent preparation for preventing and treating Parkinson's disease: China, CN114047281. 2022-02-15.
