5988-19-2
Chemical Structure
L-Dihydroorotic acid
- CAS No.: 5988-19-2
- Formula:C5H6N2O4
- Molecular Weight:158.11
IUPAC Name: (S)-2,6-dioxohexahydropyrimidine-4-carboxylic acid
InChIKey: UFIVEPVSAGBUSI-REOHCLBHSA-N
SMILES: O=C([C@H](CC(N1)=O)NC1=O)O
Biological Activity: L-Dihydroorotic acid is an important intermediate in the metabolism of orotic acid and a substrate of dihydroorotate dehydrogenase (DHODH). L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme[1][2].
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L-Dihydroorotic acid | 99.97% | L-Dihydroorotic acid is an important intermediate in the metabolism of orotic acid and a substrate of dihydroorotate dehydrogenase (DHODH). L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme. | ||||||||||||||||||||
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L-Dihydroorotic acid (Standard) | 99.99% | L-Dihydroorotic acid (Standard) is an analytical reference standard for L-Dihydroorotic acid. This product is used for research and analytical applications. L-Dihydroorotic acid is an important intermediate in the metabolism of orotic acid and a substrate of dihydroorotate dehydrogenase (DHODH). L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme. | ||||||||||||||||||||
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- [1]. St. Louis, Missouri,et al. ENZYMATIC SYNTHESIS AND BREAKDOWN OF A PYRIMIDINE, OROTIC ACID.October 28, 1953.
- [2]. Yin F, et al. Quantitation of uridine and L-dihydroorotic acid in human plasma by LC-MS/MS using a surrogate matrix approach. J Pharm Biomed Anal. 2021 Jan 5;192:113669. [Content Brief]