607-91-0
Chemical Structure
Myristicin
Synonym(s): Myristicine
- CAS. Nr.: 607-91-0
- Formula:C11H12O3
- Molecular Weight:192.21
IUPAC Name: 6-allyl-4-methoxybenzo[d][1,3]dioxole
InChIKey: BNWJOHGLIBDBOB-UHFFFAOYSA-N
SMILES: C=CCC1=CC(OC)=C2OCOC2=C1
Biological Activity: Myristicine is an orally bioavailable serotonin receptor antagonist and weak monoamine oxidase (MAO) inhibitor. Myristicine also exerts anti-cancer effects on gastric cancer cells by inhibiting the EGFR/ERK signaling pathway. Myristicine is the main component of nutmeg essential oil and has anti-cancer, anti-proliferative, antibacterial, anti-inflammatory and apoptosis-inducing effects. Myristicine abuse can produce hallucinogenic effects, organ damage, etc[1][2][3][4].
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Myristicin | 99.54% | Myristicine is an orally bioavailable serotonin receptor antagonist and weak monoamine oxidase (MAO) inhibitor. Myristicine also exerts anti-cancer effects on gastric cancer cells by inhibiting the EGFR/ERK signaling pathway. Myristicine is the main component of nutmeg essential oil and has anti-cancer, anti-proliferative, antibacterial, anti-inflammatory and apoptosis-inducing effects. Myristicine abuse can produce hallucinogenic effects, organ damage, etc. | ||||||||||||||||||||
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Myristicin (Standard) | ≥98% | Myristicin (Standard) is the analytical standard of Myristicin. This product is intended for research and analytical applications. Myristicine is an orally bioavailable serotonin receptor antagonist and weak monoamine oxidase (MAO) inhibitor. Myristicine also exerts anti-cancer effects on gastric cancer cells by inhibiting the EGFR/ERK signaling pathway. Myristicine is the main component of nutmeg essential oil and has anti-cancer, anti-proliferative, antibacterial, anti-inflammatory and apoptosis-inducing effects. Myristicine abuse can produce hallucinogenic effects, organ damage, etc. | ||||||||||||||||||||
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- [1]. Kalbhen DA, et al. Nutmeg as a narcotic. A contribution to the chemistry and pharmacology of nutmeg (Myristica fragrans).Angew Chem Int Ed Engl. 1971 Jun;10(6):370-4. [Content Brief]
- [2]. Dawidowicz AL, et al. Simple and rapid determination of myristicin in human serum.Forensic Toxicol. 2013 Jan;31(1):119-123. Epub 2012 Aug 15. [Content Brief]
- [3]. Badr G, Elsawy H, Amalki M A, et al. Protective effects of myristicin against ulcerative colitis induced by acetic acid in male mice[J]. Food and Agricultural Immunology, 2020, 31(1): 435-446.
- [4]. Song J, et al. Myristicin Suppresses Gastric Cancer Growth via Targeting the EGFR/ ERK Signaling Pathway. Curr Mol Pharmacol. 2023;16(7):712-724. [Content Brief]
Keywords
