607-91-0
607-91-0
Chemical Structure
Myristicin
Synonym(s): Myristicine
- CAS. Nr.: 607-91-0
- Formula:C11H12O3
- Molecular Weight:192.21
IUPAC Name: 6-allyl-4-methoxybenzo[d][1,3]dioxole
InChIKey: BNWJOHGLIBDBOB-UHFFFAOYSA-N
SMILES: C=CCC1=CC(OC)=C2OCOC2=C1
Biological Activity: Myristicine is an orally bioavailable serotonin receptor antagonist and weak monoamine oxidase (MAO) inhibitor. Myristicine also exerts anti-cancer effects on gastric cancer cells by inhibiting the EGFR/ERK signaling pathway. Myristicine is the main component of nutmeg essential oil and has anti-cancer, anti-proliferative, antibacterial, anti-inflammatory and apoptosis-inducing effects. Myristicine abuse can produce hallucinogenic effects, organ damage, etc[1][2][3][4].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Myristicin | 99.48% | Myristicine is an orally bioavailable serotonin receptor antagonist and weak monoamine oxidase (MAO) inhibitor. Myristicine also exerts anti-cancer effects on gastric cancer cells by inhibiting the EGFR/ERK signaling pathway. Myristicine is the main component of nutmeg essential oil and has anti-cancer, anti-proliferative, antibacterial, anti-inflammatory and apoptosis-inducing effects. Myristicine abuse can produce hallucinogenic effects, organ damage, etc. | ||||||||||||||||||||
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Myristicin (Standard) | ≥98% | Myristicin (Standard) is the analytical standard of Myristicin. This product is intended for research and analytical applications. Myristicine is an orally bioavailable serotonin receptor antagonist and weak monoamine oxidase (MAO) inhibitor. Myristicine also exerts anti-cancer effects on gastric cancer cells by inhibiting the EGFR/ERK signaling pathway. Myristicine is the main component of nutmeg essential oil and has anti-cancer, anti-proliferative, antibacterial, anti-inflammatory and apoptosis-inducing effects. Myristicine abuse can produce hallucinogenic effects, organ damage, etc. | ||||||||||||||||||||
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Sarisan | Sarisan (Asaricin) is a phenolic derivative with antifungal and insecticidal activity. Sarisan can be found in the stem bark of Ocotea opifera Mart.. | |||||||||||||||||||||
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Eugenol (Standard) | 99.87% | Eugenol (Standard) is the analytical standard of Eugenol. This product is intended for research and analytical applications. Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation. | ||||||||||||||||||||
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Dihydromyristicin | Dihydromyristicin, a plant flavonoid, has potent anti-inflammatory properties. Dihydromyristicin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-κB signaling pathways. | |||||||||||||||||||||
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Anthriscinol | Anthriscinol is a natural product that can be isolated from Anthriscus sylvestris HOFFM. | |||||||||||||||||||||
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3-Methoxy-4,5-methylenedioxycinnamaldehyde | 3-Methoxy-4,5-methylenedioxycinnamaldehyde is a Phenylpropanoids product that can be isolated from the herbs of Artemisia annua L.. | |||||||||||||||||||||
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Croweacin | Croweacin is a phenylpropanoid compound found in Myristica fragrans Houtt and other species, with antibacterial and corrosion-inhibiting activities. Croweacin acts as a corrosion inhibitor by providing or donating electrons to the brass surface to form a protective layer that blocks aggressive ions. Croweacin can be used in research related to green corrosion inhibitors. | |||||||||||||||||||||
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Elemicin (Standard) | ≥98% | Elemicin is an orally active alkenylbenzene widely distributed in many herbs and spices. Elemicin inhibits Stearoyl-CoA Desaturase 1 (SCD1) by metabolic activation. Elemicin has anti-influenza activities, antimicrobial, antioxidant, and antiviral activities. Elemicin and its reactive metabolite of 1′-Hydroxyelemicin can induce hepatotoxicity. | ||||||||||||||||||||
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Methyl kakuol | 99.95% | Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM. | ||||||||||||||||||||
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Antioxidant agent-4 | 96.0% | Antioxidant agent-4 (Compound 2) is an effective antioxidant molecule with antilipid peroxidative activity. | ||||||||||||||||||||
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Lophophine hydrochloride | Lophophine hydrochloride is the drug intermediate of anhalonine and Lophophorine (HY-119478), and can be found in Lophophora diffusa. Anhalonine causes slight sleepiness in frog. Lophophorine causes long-lasting convulsions, reflex excitability, muscle stiffness, and paralysis in rabbit and frog model. | |||||||||||||||||||||
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References
- [1]. Kalbhen DA, et al. Nutmeg as a narcotic. A contribution to the chemistry and pharmacology of nutmeg (Myristica fragrans).Angew Chem Int Ed Engl. 1971 Jun;10(6):370-4. [Content Brief]
- [2]. Dawidowicz AL, et al. Simple and rapid determination of myristicin in human serum.Forensic Toxicol. 2013 Jan;31(1):119-123. Epub 2012 Aug 15. [Content Brief]
- [3]. Badr G, Elsawy H, Amalki M A, et al. Protective effects of myristicin against ulcerative colitis induced by acetic acid in male mice[J]. Food and Agricultural Immunology, 2020, 31(1): 435-446.
- [4]. Song J, et al. Myristicin Suppresses Gastric Cancer Growth via Targeting the EGFR/ ERK Signaling Pathway. Curr Mol Pharmacol. 2023;16(7):712-724. [Content Brief]
