621-72-7
Chemical Structure
Bendazol
- CAS No.: 621-72-7
- Formula:C14H12N2
- Molecular Weight:208.26
IUPAC Name: 2-benzyl-1H-benzo[d]imidazole
InChIKey: YTLQFZVCLXFFRK-UHFFFAOYSA-N
SMILES: C1(CC2=CC=CC=C2)=NC3=CC=CC=C3N1
Biological Activity: Bendazol is an orally effective antihypertensive agent. Bendazol acts directly on vascular smooth muscle to dilate blood vessels and reduce peripheral resistance, thereby improving blood circulation. Bendazol significantly inhibits the development of myopia in rabbit models. Bendazol can regulate kidney function by increasing the activity of NO synthase in the rat model of nephrogenic hypertension. In addition, Bendazol has an effect on sexual behavior and spermatogenesis in male rats[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bendazol | 99.60% | Bendazol is an orally effective antihypertensive agent. Bendazol acts directly on vascular smooth muscle to dilate blood vessels and reduce peripheral resistance, thereby improving blood circulation. Bendazol significantly inhibits the development of myopia in rabbit models. Bendazol can regulate kidney function by increasing the activity of NO synthase in the rat model of nephrogenic hypertension. In addition, Bendazol has an effect on sexual behavior and spermatogenesis in male rats. | ||||||||||||||||||||
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- [1]. Tong L, et al. Topical bendazol inhibits experimental myopia progression and decreases the ocular accumulation of HIF-1α protein in young rabbits. Ophthalmic Physiol Opt. 2020 Sep;40(5):567-576. [Content Brief]
- [2]. Eliseeva EV, et al. Effect of Hypotensive Drugs on Dynamics of Nitroxide-Producing Renal Function in Rats with Nephrogenic Hypertension. Bull Exp Biol Med. 2017 Jan;162(3):357-361. [Content Brief]
- [3]. Kuzubova EA, et al. [Effect of dibazol (bendazol) on the generative function in rats]. Eksp Klin Farmakol. 2007 Mar-Apr;70(2):37-9. [Content Brief]
Keywords
