63335-24-0
Chemical Structure
Malabaricone B
- CAS No.: 63335-24-0
- Formula:C21H26O4
- Molecular Weight:342.43
IUPAC Name: 1-(2,6-dihydroxyphenyl)-9-(4-hydroxyphenyl)nonan-1-one
InChIKey: KOAPDMKKECXPHX-UHFFFAOYSA-N
SMILES: O=C(C1=C(O)C=CC=C1O)CCCCCCCCC2=CC=C(O)C=C2
Biological Activity: Malabaricone B, a naturally occurring plant phenolic, is an orally active α-glucosidase inhibitor with an IC50 of 63.7 µM. Malabaricone B has anticancer, antimicrobial, anti-oxidation and antidiabetic activities[1][2][3].
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Malabaricone B | 99.93% | Malabaricone B, a naturally occurring plant phenolic, is an orally active α-glucosidase inhibitor with an IC50 of 63.7 µM. Malabaricone B has anticancer, antimicrobial, anti-oxidation and antidiabetic activities. | ||||||||||||||||||||
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Similarity Score 0.85
HY-N9973Malabaricone A -
Similarity Score 0.84
HY-N8518RMalabaricone C (Standard) -
Similarity Score 0.66
HY-N0142Phloretin -
Similarity Score 0.66
HY-W983015Davidigenin -
Similarity Score 0.66
HY-N9240Acerogenin G -
Similarity Score 0.65
HY-15887MG 149 -
Similarity Score 0.64
HY-1871441-(2,4,6-Trihydroxyphenyl)-1-octanone -
Similarity Score 0.64
HY-N7314Asebogenin -
Similarity Score 0.63
HY-N89274'-O-Demethylbroussonin A -
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References
- [1]. Mrityunjay Tyagi, et al. Spice-derived phenolic, malabaricone B induces mitochondrial damage in lung cancer cells via a p53-independent pathway. Food Funct. 2018 Nov 14;9(11):5715-5727. [Content Brief]
- [2]. K Y Orabi, et al. Isolation and characterization of two antimicrobial agents from mace (Myristica fragrans). J Nat Prod. May-Jun 1991;54(3):856-9. [Content Brief]
- [3]. B Prabha, et al. Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair. Bioorg Med Chem. 2018 Jul 23;26(12):3461-3467. [Content Brief]