Isolation and characterization of two antimicrobial agents from mace (Myristica fragrans)

  • J Nat Prod. 1991 May-Jun;54(3):856-9. doi: 10.1021/np50075a017.
K Y Orabi  1 J S Mossa F S el-Feraly
Affiliations
  • 1. Department of Pharmacognosy and Medicinal, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Abstract

The two antimicrobial resorcinols malabaricone B [1] and malabaricone C [2] were isolated from mace, the dried seed covers of Myristica fragrans. Both compounds exhibited strong Antifungal and Antibacterial activities. Structure modifications by methylation or reduction resulted in diminished activity.

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