641-74-7
641-74-7
Chemical Structure
Isomannide
Synonym(s): 1,4:3,6-Dianhydromannitol
- CAS No.: 641-74-7
- Formula:C6H10O4
- Molecular Weight:146.14
IUPAC Name: (3R,3aR,6R,6aR)-hexahydrofuro[3,2-b]furan-3,6-diol
InChIKey: KLDXJTOLSGUMSJ-KVTDHHQDSA-N
SMILES: O[C@H]1[C@]2([H])[C@@](OC1)([H])[C@@H](CO2)O
Biological Activity: Isomannide (1,4:3,6-Dianhydromannitol) is a common intermediate compound and derivative of Isosorbide (HY-B1469). Some derivatives of isomannide have potent inhibitory effects on KLK5 and KLK7. Isomannide can be used in the research of HCV infection and KLK5/KLK7-related diseases[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Isomannide | 99.44% | Isomannide (1,4:3,6-Dianhydromannitol) is a common intermediate compound and derivative of Isosorbide (HY-B1469). Some derivatives of isomannide have potent inhibitory effects on KLK5 and KLK7. Isomannide can be used in the research of HCV infection and KLK5/KLK7-related diseases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Rose M, et al. Isosorbide as a renewable platform chemical for versatile applications--quo vadis? ChemSusChem. 2012 Jan 9;5(1):167-76. [Content Brief]
- [2]. Barros TG, et al. Pseudo-peptides derived from isomannide: inhibitors of serine proteases. Amino Acids. 2010 Mar;38(3):701-9. [Content Brief]
- [3]. Oliveira JP, et al. Isomannide-based peptidomimetics as inhibitors for human tissue kallikreins 5 and 7. ACS Med Chem Lett. 2013 Dec 6;5(2):128-32. [Content Brief]
Keywords
