6468-55-9
6468-55-9
Chemical Structure
Demethylwedelolactone
- CAS No.: 6468-55-9
- Formula:C15H8O7
- Molecular Weight:300.22
IUPAC Name: 1,3,8,9-tetrahydroxy-6H-benzofuro[3,2-c]chromen-6-one
InChIKey: LUTYTNLPIUCKBJ-UHFFFAOYSA-N
SMILES: O=C1C2=C(OC3=CC(O)=C(O)C=C32)C4=C(O)C=C(O)C=C4O1
Biological Activity: Demethylwedelolactone is a naturally occurring coumestan isolated from Eclipta alba. Demethylwedelolactone is a potent trypsin inhibitor with an IC50 of 3.0 μM. Demethylwedelolactone suppresses cell motility and cell invasion of breast cancer cell[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Demethylwedelolactone | 99.89% | Demethylwedelolactone is a naturally occurring coumestan isolated from Eclipta alba. Demethylwedelolactone is a potent trypsin inhibitor with an IC50 of 3.0 μM. Demethylwedelolactone suppresses cell motility and cell invasion of breast cancer cell. | ||||||||||||||||||||
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References
- [1]. Syed SD, et al. Trypsin inhibitory effect of wedelolactone and demethylwedelolactone. Phytother Res. 2003 Apr;17(4):420-1. [Content Brief]
- [2]. Lee YJ, et al. Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. Eur J Med Chem. 2012 Oct;56:361-7. [Content Brief]
