Lupinalbin A
Lupinalbin A (Boeravinone L) is a dipeptidyl peptidase 4 (DPP4) and α-glucosidase inhibitor with IC50 values of 45.2 and 53.4 µM, respectively. Lupinalbin A exhibits antidiabetic activity.
For research use only. We do not sell to patients.
- CAS No.: 98094-87-2
- Formula: C15H8O6
- Molecular Weight:284.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
DPP-4 45.2 μM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
>1 μM
Compound: 2
|
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells pretreated for 1 hr followed by LPS-stimulation and measured after 24 hrs by Griess assay
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells pretreated for 1 hr followed by LPS-stimulation and measured after 24 hrs by Griess assay
|
[PMID: 29932657] |
Chemical Information
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CAS No. 98094-87-2
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Molecular Weight 284.22
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Formula C15H8O6
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SMILES
O=C1C2=C(OC3=CC(O)=CC=C32)OC4=CC(O)=CC(O)=C14
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Synonyms
Boeravinone L
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)